Test 2 Flashcards
what antibodies make up the ABO system
IgG & IgM
which antibody reacts at body temperature
IgM
Do antibodies present WITHOUT previous red cell stimulation
yes
when are antibodies presented in the body
first few months after birth
what are the Landsteiner’s rules
- YOU MUST BE NEGATIVE FOR THE ANTIGEN IN ORDER TO BUILD THE ANTIBODY
- YOU DON’T BUILD ANTIBODIES TO YOUR OWN ANTIGENS (this is generally true, except in autoimmune disease)
what gene is a amorph
O gene
Inheritance of an A gene causes what
A antigen on red cells
inheritance of an B gene causes what
B antigen on red cells
What do Group O have on red cells
no antigens
what do group AB have on their cells
A and B antigen
what antibody do Group A have in their plasma
anti-B
what antibody do Group B have in their plasma
anti-A
what antibody do Group B have in their plasma
anti- A anti B & anti-A,B
In the American Caucasian population, Group O is what percentage?
45%
In the American Caucasian population, Group A is what percentage?
40%
In the American Caucasian population, Group B is what percentage?
11%
In the American Caucasian population, Group AB is what percentage?
4%
what group is the universal donor of red cells and most desired?
Group O
what do we use to detect antigens on red cells
commercially prepared antibodies
what do we use to detect the antibodies in the plasma?
commercially prepared A1 and B cells
what determines the ABO group (forward Grouping)
the antigens on red cells
what confirms the ABO grouping
antibodies in the patients plasma (Reverse grouping, also called Backtype)
ANTI-A (4+), ANTI-B (0), ANTI-A,B (4+), A1 CELLS (0), B CELLS (4+)
Group A
ANTI-A (0), ANTI-B (4+), ANTI-A,B (4+), A1 CELLS (4+), B CELLS (0)
Group B
