Telencephalon Flashcards
Anatomically, R and L cerebral hemispheres are
Equivalent
Pallium
Outer convoluted gray cerebral cortex
Centrum semiovale
Underlying mass of white fibers
Basal ganglia
Deep within white matter; collections of neuron cell bodies
Lobes are named for
Overlying bones
Largest lobe
Frontal lobe
Smallest lobe
Occipital lobe
Functions of telencephalon
- Final integration of neural mechanisms
- Initiation center for voluntary actions
- Memory and associative memory
- Abstract thinking - basis of emotional response
Thickest part of cortex
Precentral gyrus
Thinnest part of cortex
Calcarine sulcus
Subdivisions of cortex
Neocortex
Allocortex
Neocortex
Phylogenetically new
Occupies 90% of cortex
6 Laminae of neocortex
- Molecular lamina I
- External granular lamina II
- External pyramidal lamina III
- Internal granular lamina IV
- Internal pyramidal lamina V
- Multiform lamina VI
Molecular layer
Lamina I
Outermost lamina (nearest pia mater) Filled with synaptic activity
External granular layer
Lamina II
Small, closely packed granular neurons
Axons extend into deeper lamina of same cortex (does not reach white matter)
Aka Intracortical Association Layer
External pyramidal layer
Lamina III
Small pyramidal neuron cell bodies
Axons extend out of cortex to white matter, then return to gray
Aka Intercortical Association Layer
External granular layer + external pyramidal layer
Thinking part of cortex
Associative Cortex
Internal granular layer
Lamina IV
Thalamic inputs arrive here
Well developed in sensory areas
Internal pyramidal layer
Lamina V
Large pyramidal shaped neuron cell bodies (includes Betz cells)
Axons project to other brain and cord centers from here (corticospinal and corticobulbar fibers)
Multiform layer
Lamina VI
Mix of incoming and outgoing fibers
Lamina V + lamina VI
Projection laminae
Brodmann Area #4 confined to
Precentral gyrus of frontal lobe
Brodmann Area #4
Function
Voluntary motor initiation, especially in distal extremities, facial and oral musculature
Only area to contain Betz cells
Brodmann area #4
Brodmann area #4 has well developed ___ laminae
Projection
V and VI
No other single area contributes more fibers to pyramidal system than the
Precentral gyrus
Brodmann areas 1, 2, 3
Location
Post central gyrus of parietal lobe
Brodmann areas 1, 2, 3
Function
Somesthetic cortex (body sensing) Pain, thermal, deep and light touch, vibratory, kinesthetic input received and integrated into conscious sensation
Specific thalamic efferent from __ and ___ are abundant in areas 1, 2, 3
VPL
VPM
Lamina __ is well developed in areas 1,2,3
IV
Also projection cortex; V, VI
Areas 6 and 8
Location
Just in front of area #4
Areas 6 and 8 also referred to as
Premotor regions
Areas 6 and 8 are good ___ and contribute fibers directly and indirectly to pyramidal system
Motor initiation centers
Area #6
Function
Influence on proximal portions of extremities (hips and shoulders)
Area #8
Function
Initiates voluntary movements of eyes
Fibers from #8 stimulate LMN that move 6 extraocular eye muscles
Location of LMN that move extraocular eye muscles
Nuclei of CN III, IV, VI
Areas 9, 10, 11, 12 known as
Prefrontal region
Newest of neopallial structures
Areas 9, 10, 11, 12
Areas 9, 10, 11, 12 have highly developed ___ and associative input arrives from all cortical regions
Associative cortex (lamina II, III)
Areas 9, 10, 11, 12
Function
Elaboration of thought
Abstract reasoning
Imagination
Emotions
Area #44 also referred to as
Broca’s Speech Area
Area #44 location
Frontal operculum along lateral inferior surface of frontal lobe
Broca’s Speech Area
Function
Motor speech center
Area #44 directs area #4 neurons that initiate
Tongue, laryngeal, and pharyngeal musculature in process of speaking
Frequently affected in strokes due to middle cerebral artery
Area #44
Aphasia
Loss of power to communicate through writing, speaking, or signs
Damage to Broca’s area results in
Motor aphasia
Dysphasia
Partial or unusual loss of communicative ability
Speech is dominant on __ side of brain
Left
If area 44 is damaged on non-dominant side, patient will have difficulty with…
Prosodic language
Areas 17, 18,19 occupy
Bulk of cortex in occipital lobe
Areas 17,18,19 collectively make up
Visual cortex
Area 17 located along
Calcarine sulcus
Area 17 receives fiber input from
Lateral geniculate body
Area 17 is..
Primary visual cortex
Number 17 also called ____ due to white band running through Lamina IV
Striate cortex
We “see” in area __
17
*includes perception of motion, illumination, transparency
Areas 18 and 19 integrate and store ___
Visual memories
Help recognize what we see
Prosopagnosia
Difficulty remembering/recognizing faces
Area 41 is the
Primary Auditory Cortex
Area 41 located within
Superior temporal gyrus, especially along Heschl’s gyrus/ transverse temporal gyrus
Area 41 receives input from
Medial geniculate bodies
We “hear” in area
41
*includes pitch, tone, loudness
Wernicke’s area
Area 22
___ surrounds area 41
Wernicke’s area
Wernicke’s area primarily known for its
Hearing memory function
Importance in speech
Syntax
Grammar
Light striking medial side of retina comes from ___
Lateral field of vision
Optic chiasm segregates
Visual field
Left field of vision goes to
Right side of brain
Right field of vision goes to
Left side of brain
Damage to optic chiasm would result in
Loss of peripheral vision
Areas 5,7,39,40 fill bulk of
Parietal lobe
Areas 5,7,39,40 function
Reading
Writing
Language
Area 39 located in
Angular gyrus
Lesion in area 39 could result in
Alexia
Agraphia
Alexia
Deficiency in reading
Agraphia
Deficiency in writing
Connection between Wernicke’s and Broca’s area
Arcuate fasciculus
Area 43 function
Gustatory center
Area 43 located in
Parietal operculum
Interpretation of olfaction occurs in
Area 34 in the uncus
Area 28 in parahippacampal gyrus
Functions typically lateralized to left
Speech Vocabulary Grammar Linear reasoning Tool use
Functions typically lateralized to right
Singing
Spatial manipulations
Prosodic language
Caudate nucleus + putamen nucleus
Neostraitum
Caudate nucleus + putamen nucleus + globus pallidus
Corpus striatum
Caudate nucleus + putamen nucleus + globus pallidus + amygdaloid complex
Basal ganglia
Putamen + globus pallidus
Lenticular nucleus
Thickness of cortex varies between
1.5-4.5 mm
Parts of caudate nucleus
Head
Body
Tail
Head region of caudate nucleus continuous with
Putamen nucleus
Via gray matter bridges
Caudate efferent output fibers
Putamen
Globus pallidus
Substantia nigra
Thalamus
Most lateral of corpus striatal nuclei
Putamen nucleus
Efferent output fibers of putamen nucleus
Globus pallidus
Substantia nigra
Thalamus
Caudate
Medial medullary lamina separates
Globus pallidus into medial and lateral segments
Lateral medullary lamina separates
Lateral part of globus pallidus from putamen
Afferent fibers of globus pallidus AKA
Pallidal fibers
Afferent fibers from globus pallidus include
Caudate nucleus
Putamen nucleus
Subthalamic nucleus
Efferent fibers from globus pallidus AKA
Pallidalfugal fibers
**represent primary efferent outflow from corpus striatum
Most efferent fibers from globus pallidus go to
Anterior aspect of thalamus
Amygdala location
Temporal lobe
Amygdala inputs
Olfactory tract
Hypothalamus
Neocortex
Amygdala considered to be part of
Limbic system (emotions)
Amygdaloid activity is associated with
Increased inhibition
Amygdaloid must be intact to
Sense fear or anger
Basal ganglia plays key role in
Extrapyramidal system
Basal ganglia contributes to brain’s ability to
Inhibit pain
3 fibers types in white matter
- Projection
- Commissural
- Association
Most projection axons travel in
Corona radiata and internal capsule
Commissural axons
Connect equivalent structures on opposite hemispheres
Corpus callosum contains approximately how many neurons
300 million
Found only in placental mammals
Corpus callosum
Parts included in corpus callosum
Splenium Body Genu Rostrum Forceps anticus Forceps posticus Tapetum
Variable part of basal ganglia
Claustrum
Huntington’s Chorea
Graceful involuntary movements due to GABA deficiency
Ballism/ Hemiballism
Violent movement
Lesions in subthalamic nucleus or globus pallidus
Head region is continuous with putamen nucleus by gray matter bridges
Caudate nucleus
Most lateral of corpus straital nuclei
Putamen
Putamen stores dopamine in
Nigrostriatal axon telodendria
Globus pallidus is separated into medial and lateral segments by
Medial medullary lamina
Lateral part of globus pallidus is separated from putamen by
Lateral medullary lamina
Afferent fibers of globus pallidus
Pallidal fibers
Efferent fibers of globus pallidus
Pallidalfugal fibers
Pallidalfugal fibers represent…
Primary efferent outflow from corpus striatum
Most pallidalfugal fibers go to
Anterior aspect of thalamus
Inputs to amygdala are from
Olfactory tract
Amygdala considered to be part of
Limbic system
Amygdaloid activity associated with
Increased inhibition
Amygdaloid must be intact to sense
Fear and anger
Basal ganglia play a key role in __ and __
Extrapyramidal system
Brain’s ability to inhibit pain
Fiber types in centrum semiovale
Projection
Commissural
Association
Most projection axons of centrum semiovale travel to __ and ___
Corona radiata
Internal capsule
Corpus callosum contains ___ neurons
300 million
__ found only in placental mammals
Corpus callosum
Largest commissural axon
Corpus callosum
Parts of corpus callosum
Splenium, body, Genu, rostrum, forceps anticus, forceps posticus, tapetum