Team Based Learning Flashcards
Function of the jejunum
Absorb digested nutrients
Plicae circulares
Folds of the mucosa and submucosa
4 layers of the jejunum
Mucosa
Submucosa
Muscularis propria
Serosa
3 layers of the mucosa
Epithelium (has enterocytes, goblet cells, Paneth cells, and neuroendocrine cells) Lamina propria (CT, lymphocytes, capillaries, lymphatic channels) Muscularis mucosae
How many layers of muscle does the muscularis propria have?
2
Mesothelium
Simple squamous epithelium that lines the abdominal and thoracic organs
On the outsider of the serosa
Skin main functions
Barrier
Regulates body temperature (sweat, controls blood flow to the skin)
3 layers of the skin
Epidermis
Dermis
Hypodermis
Rete ridges
Protrusions of the epidermis into the dermis
Dermal papillae
Protrusions of the dermis into the epidermis
Adnexal structures (3)
Hair follicles
Eccrine sweat glands
Apocrine sweat glands
Protrude into the dermis and hypodermis
Hair follicles
Have sebaceous glands that secrete sebum
Also have smooth muscle bundles so hair can stand up
Eccrine sweat gland
Has secretory coli at its base and a duct that extends onto the surface of the skin
Apocrine sweat glands
Connect to a hair follicle
Located in the axillae, anogenital areas, mammary region, eyelid, and external ear canal
2 layers of the dermis
Papillary dermis (has dermal papillae, contains thin collagen fibers) Reticular dermis (contains thick collagen fibers)
4 types of tissue
Epithelia
Connective
Muscle
Nervous
3 phases of wound healing
Inflammatory
Proliferative
Remodelling
Inflammatory phase
Damaged blood vessels cause fibrillary collagen to be exposed
Activates platelets and the coagulation cascade to form a fibrin clot
Serves as a matrix for later migration of macrophages, fibroblasts, and keratinocytes into the wound
Coagulation cascade releases chemokines (attract neutrophils and macrophages)
Neutrophils kill bacteria, macrophages kill, remove debris, and dead neutrophils
Proliferative phase
Keratinocytes at the edge of the wound migrate into the wound
Proximal keratinocytes proliferate
Endothelial cells from blood vessels migrate and proliferate (angiogenesis)
Fibroblasts migrate and proliferate (then produce matrix proteins to reconstitute the CT)
Granulation (appearance of proliferation)
Fibroblasts also alter their gene expression in order to become myofibroblasts (capable of contracting) – to close wound
Remodelling phase
Matrix proteins continue to be deposited and are also digested
Continues until the matrix resembles pre injury matrix
Healing by primary intention
Acute wounds heal faster when you bring the edges together with sutures or steristrips
Healing by secondary intention
When the edges are not brought together
Purpose of occlusive dressings
Maintain a moist environment
This helps cell migration