TDM part 2 Flashcards
1
Q
COPD : chronic obstructive pulmonary disease
First phase : bronchoconstriction
bronchodilators
Second phase : inflammation
steroids
A
Asthma
2
Q
For moderate or severe asthma attacks
Bronchodilator, vasodilator
Stimulates respiration and strengthens the action of cardiac muscles
CNS stimulant
Oral or IV form
A
Theophylline
3
Q
Pharmacokinetics
Metabolite: 3-methyl-xanthine
Drug interactions:
Phenytoin, carbamazepine
Erythromycin
A
Theophylline
4
Q
Theophylline
Adult therapeutic range: ________
A
10-20ug/mL
5
Q
Newborns : __________
A
5-10ug/mL
6
Q
Toxicity :
15-20 ug/mL
A
Nausea, vomiting, headache and anxiety
7
Q
20-40 ug/mL
A
Tachycardia, arrhythmias
8
Q
> 40 ug/mL
A
Seizures, cardiac arrest
