Chemotherapeutic agents Flashcards
1
Q
Inhibits dihydrofolate reductase (DNA synthesis)
Toxicity : hematologic effects, GI effects
A
Methotrexate
2
Q
Uses of Methotrexate
A
Psoriasis
Refractory rheumatoid arthritis
Malignant neoplastic diseases
3
Q
Treat leukemias and lymphomas prior to BM transplantation
Toxicity : hepatic veno-occlusive disease
A
Busulfan