Chemotherapeutic agents Flashcards

1
Q

Inhibits dihydrofolate reductase (DNA synthesis)

Toxicity : hematologic effects, GI effects

A

Methotrexate

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2
Q

Uses of Methotrexate

A

Psoriasis
Refractory rheumatoid arthritis
Malignant neoplastic diseases

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3
Q

Treat leukemias and lymphomas prior to BM transplantation

Toxicity : hepatic veno-occlusive disease

A

Busulfan

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