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Endo Week 3 > TCA Cycle and ETC > Flashcards

TCA Cycle and ETC Flashcards

1
Q

what is pyruvate turned into to enter TCA?

A

acetyl coa

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2
Q

what is enzyme that turns pyruvate into TCA?

A

pyruvate dehydrogenase

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3
Q

what does acetly coa join to make citrate in step one of TCA?

A

oxaloacetate

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4
Q

how many NADH does TCA make

A

3

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5
Q

how many FADH2 does TCA make

A

1

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6
Q

how many GTP does TCA make?

A

1

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7
Q

what is enzyme that makes citrate in TCA?

A

citrate synthase

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8
Q

what comes after citrate in TCA?i

A

isocitrate

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9
Q

what is isocitrate turned into in TCA?

A

a ketoglutorate

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10
Q

What is enzyme that turns isocitrate into a ketoglutarate?

A

isocitrate dehydrogenase

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11
Q

what comes out of TCA during isocitrate dehdrogenase rxn?

A

CO2 and NADH

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12
Q

what is a ketoglutarate turned into in TCA?

A

succinyl CoA

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13
Q

what is enzyme that turns a ketoglutarate into succinyl coa?

A

a ketoglutarate dehdryogenase

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14
Q

what comes off during a ketoglutarate dehydrogenase turning a keto into succinyl coa?

A

CO2 and NADH

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15
Q

what is succinyl coa turned into?

A

succinate

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16
Q

what is succinate turned into?

A

fumarate

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17
Q

what enzymes activates succinate into fumarate?

A

succinate dehydrogenase

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18
Q

what comes off during succinate dehydrogenase rxn?

A

FADH 2

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19
Q

what is fumarate made into?

A

malate

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20
Q

what is malate made into?

A

oxaloacetate

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21
Q

what is enzyme that makes malate inot oxaloacetate?

A

malate dehydrogenase

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22
Q

what comes off during malate dehdryogenase rxn?

A

NADH

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23
Q

what three things highly regulate pyruvate dehydrogenase?

A

ATP, NADH and acetyl CoA (all if high inhibit)

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24
Q

what are the two main rate limiting enzymes in the TCA cycle?

A

a ketoglutarate dehydrogenase and isocitrate dehydrogenase

25
Q

how many complexes in ETC?

A

4

26
Q

what is name of complex I in ETC?

A

NADH-Q oxireductase

27
Q

what is name of complex II in ETC?

A

succinate Q reductase

28
Q

complex I takes electrons from what molecule?

A

NADH

29
Q

what does complex I give NADH electrons to?

A

ubiquinone

30
Q

where does ubiquinone take NADH electrons from complex I

A

to complex III

31
Q

what is name of complex III in ETC?

A

Q-cytochrome c oxireductase

32
Q

what molecule does complex II take electrons from?

A

FADH2

33
Q

where do electrons from complex II get passed to?

A

ubiquinone and to complex III

34
Q

what takes electrons from complex III to IV?

A

cytochrome C

35
Q

what happens at complex IV?

A

cytochrome C is oxidized and O2 turned into H20 via electrons

36
Q

how manY h+ is pumped at complex I?

A

4

37
Q

how manY h+ is pumped at complex II?

A

0

38
Q

how manY h+ is pumped at complex III?

A

2

39
Q

how manY h+ is pumped at complex IV?

A

4

40
Q

what is another name for complex IV?

A

cytochrome C oxidase

41
Q

what is complex V?

A

ATO synthase

42
Q

what are the two divisions of ATP synthase?

A

Fo anf F1

43
Q

where is Fo?

A

in inner membrane of mitochondria

44
Q

where is F1?

A

in inner cytoplasm of mitochondria

45
Q

what is the fxn of Fo of ATP synthase?

A

8-14 c subunits that are the proton channel

46
Q

what subunit of F1 is in charge of producing and releasing the ATP?

A

Beta

47
Q

what are the three states that beta subunit of F1 f ATP synthase can be in?

A

L O and T

48
Q

what is the L state of the B subunit?

A

beta binds ADP and P

49
Q

what is the T form of the B subunit?

A

ATP is made

50
Q

what is the O form of the B subunit?

A

ATP is Off (released)

51
Q

what subunit of F1 of ATP synthase is in charge of rotating B subunit through different states?

A

gamma subunit

52
Q

what is total ATP from one glucose?

A

30

53
Q

how many ATP from glycolysis?

A

net of 2

54
Q

how many ATP from TCA cycle?

A

2 ATP

55
Q

how many NADH made in glycolysis?

A

2 NADH

56
Q

how many NADH in TCA cycle from 2 acetyl CoAs?

A

6 NADH

57
Q

how many FADH2in TCA cycle from 2 acetyl CoAs?

A

2 FADH2

58
Q

how many NADH from decarboxylation of pyruvate into acetyl coa?

A

2 NADH

Endo Week 3 (8 decks)

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