Diabetes Pathophys

Question 1

how high is A1C in diabetes diagnosis

Answer 1

greater then 6.5

Question 2

how high is fasting plasma glucose in diabetes diagnosis?

Answer 2

greater than 126 mg/dl

Question 3

how high is 2 hr plasma gluose during OGTT for diagnosis of diabetes?

Answer 3

greater than 200

Question 4

a random plasma glucose higher than what is sufficient for diabetes diagnosis?

Answer 4

200 mg/dl

Question 5

what is OGTT?

Answer 5

oral glucose tolerance test

Question 6

what is A1c in pre diabetes?

Answer 6

5.7-6.4

Question 7

what is 2 hr plasma glucose during OGTT in pre diabetes?

Answer 7

140-199

Question 8

what is free plasma glucose in pre diabetes?

Answer 8

100-125

Question 9

at what age shoudl diabetes testing begin?

Answer 9

at 45, especially for anyone overweight

Question 10

if someone has prediabetes, when should they be tested for diabetes?

Answer 10

yearly

Question 11

name some risk factors for diabates

Answer 11

first degree relative
high risk race
cardiovascular disease
HTN
hyperlipidemia
obesity

Question 12

what are high risk races for diabetes?

Answer 12

AA, latine, asian, pacific islander

Question 13

when should you screen for type 2 diabetes in kids?

Answer 13

overweight with at least one risk factor

Question 14

in end of type 1 DM, will c peptide be present

Answer 14

NO

Question 15

what is most common cause of young adult/child diabetes?

Answer 15

type 1 DM

Question 16

can older adults have type 1 DM?

Answer 16

you betcha

Question 17

what type of diseases often coincide with type 1 dm?

Answer 17

other autoimmune diseases…hypothyroid most common

Question 18

what are the three antibodies you can find in type 1 DM?

Answer 18

anti-GAD,
anti-insulin (IAA)
anti0 ICA512 (islet cell antibody)

Question 19

what is most common co morbid autoimmune disease with type 1 DM?

Answer 19

hashimotos and celiac

Question 20

what does hyperglycemia in type II DM lead to with fatty acids?

Answer 20

eventually they start to accumulate and levels will rise

Question 21

what do high free fatty acid levels cause in type II DM?

Answer 21

further inhibition of insulin release

Question 22

which of type 1 or 2 DM has higher genetic contribution?

Answer 22

type II more common to have genetic component

Question 23

is ketoacidosis more common in type I or II DM?

Answer 23

type I dm

Question 24

will C peptide be present in type 2 DM?

Answer 24

yes…

Question 25

will incretin be increased or decreased in type II DM?

Answer 25

it decreases

Question 26

will glucagon be icnreased or decreased in type II DM?

Answer 26

increased

Question 27

will glucose absorption be increased or decreased in type II?

Answer 27

increased

Question 28

will lipolysis be increased or decreased in type II DM?

Answer 28

increased