TBL Modules 1-3 Questions

Question 1

What is unilateral chorea of the proximal limb?

Answer 1

hemiballismus

Question 2

Which gait is associated with cerebral stroke?

Answer 2

hemiplegic

Question 3

Which gait is associated with UMN lesion?

Answer 3

spastic diplegic

Question 4

Which gait is associated with LMN lesion?

Answer 4

neuropathic

Question 5

Which gait is associated with muscular dystrophy?

Answer 5

myopathic

Question 6

Which gait is associated with cerebellar damage?

Answer 6

ataxic

Question 7

Which gait has a steppage gait?

Answer 7

neuropathic

Question 8

Which gait has a wide based gait?

Answer 8

ataxic

Question 9

Which gait has a foot drop gait?

Answer 9

neuropathic

Question 10

Which gait has a scissor gait?

Answer 10

spastic diplegic

Question 11

Which tremor associated with Parkinson’s disease involves the fingers and thumb?

Answer 11

pill rolling tremor

Question 12

Which condition presents with Kayser Fleischer Rings?

Answer 12

wilson’s disease

Question 13

This rare pathology is often misdiagnosed as early parkinson’s disease until it affects the vertical gaze

Answer 13

progressive supranuclear palsy

Question 14

How does abnormal huntingtin protein effect the body?

Answer 14

causes premature cell death

Question 15

These lab findings are associated with wilson’s disease EXCEPT:
A) high serum levels of copper
B) face of the panda on MRI
C) liver biopsy confirming damage to copper toxicity
D) kayser fleischer rings

Answer 15

D) kayser fleischer rings

(this is a finding for wilson’s disease but its an observation not a lab finding!!!)

Question 16

Which sign is a result of a bradykinesia combined with muscle rigidity in parkinson’s disease?
A) hypophonia
B) mask like face
C) resting tremor
D) stooped posture

Answer 16

B) mask like face

Question 17

Which 2 conditions are known to be genertically inherited?
A) huntingtons
B) progressive supranuclear palsy
C) wilsons
D) parkinsons

Answer 17

A) huntingtons & C) wilsons

Question 18

Which condition is associated with alpha synuclein inclusion bodies killing neurons?

Answer 18

parkinsons

Question 19

Which of the following conditions is associated with bilateral chorea movement disorder?

Answer 19

huntingtons

Question 20

Which part of the CNS is affected in parkinsons?

Answer 20

substantia nigra

Question 21

Which part of the CNS is affected in huntingtons?

Answer 21

caudate nucleus

Question 22

Which part of the CNS is affected in wilsons?

Answer 22

putamen

Question 23

Which part of the CNS is affected in PSP?

Answer 23

CN III nuclei

Question 24

Which condition shows the prescense of tau containing inclusion bodies in neruons?
A) huntingtons
B) wilsons
C) PSP
D) parkinsons

Answer 24

C) PSP

Question 25

Which condition is associated with too many CAG repeats?

Answer 25

huntingtons

Question 26

What are the clinical triad categories associated with parkinsons disease?

Answer 26

tremor, bradykinesia, and muscle rigidity

Question 27

Wilsons disease is primarily considered a ____________ system condition

Answer 27

digestive

Question 28

How does parkinsons affect the patient's handwriting?

Answer 28

micrographia

Question 29

Parkinson's disease can present with the neck in _________ whereas PSP can present with the neck in ______________

Answer 29

flexion, extension

Question 30

Which condition does not present with a tremor? A) huntingtons B) wilsons C) PSP D) parkinsons

Answer 30

C) PSP

Question 31

Which condition shows a gross anatomical finding loss of dopaminergic neurons?

Answer 31

parkinsons

Question 32

An accumulation of neurofibrillary tangles is seen in brain neurons with?

Answer 32

PSP

Question 33

Which clinical sign is typically noticed first with alzheimers?

Answer 33

intermittent short term memory loss

Question 34

What are the lab diagnostic hallmarks of alzheimers disease?

Answer 34

beta amyloid plaque and neurofibrillary tangles

Question 35

How does aggregates of beta amyloid plaques affect nerve communication?

Answer 35

physically blocks neurotransmitters in the synapse

Question 36

Which condition only kills voluntary motor neurons?

Answer 36

ALS

Question 37

Which situation is believed to be the initial event in the onset of alzheimers?

Answer 37

aggregation of beta amyloid proteins

Question 38

What condition affects alzheimers dementia?

Answer 38

the larger the amount of neurofibrillary tangles the more severe the dementia

Question 39

What condition is the more common cause of early onset of dementia?

Answer 39

frontotemporal lobar degeneration

Question 40

All of the following pathologies are associated with abnormal tau proteins EXCEPT A) PSP B) alzheimers C) huntingtons D) picks

Answer 40

C) huntingtons

Question 41

What is the role of microglia cells in alzheimers disease?

Answer 41

clear away aggregation of beta amyloid plaques

Question 42

Which CNS structure is damaged by ALS?

Answer 42

LCST

Question 43

Which condition is an autoimmune disorder?

Answer 43

MS

Question 44

Which structure is damaged by MS?

Answer 44

myelin

Question 45

Which cranial nerves can be affected by MS?

Answer 45

optic and trigeminal

Question 46

What spinal cord gray matter is affected by ALS?

Answer 46

mostly the ventral horns

Question 47

Which regions of the world are at the greater risk for developing MS?

Answer 47

North America

Question 48

Which condition presents with personality changes preceding memory loss?

Answer 48

frontotemporal lobar dementia

Question 49

What is caused by hyperphosphorylation of tau proteins?

Answer 49

neurofibrillary tangles

Question 50

Which condition causes damage in oligodendrocytes?

Answer 50

MS

Question 51

A 32 y/o female recently moved to SC from CT. She presents in your office with a cc of intermittent muscle spasms, muscle weakness, unilateral visual impairment, and urinary incontinence. The patient reports that about a year ago she experienced similar symptoms that lasted a couple months but they went away on their own. What is this condition?

Answer 51

MS

Question 52

A 32 y/o male recently moved to SC from CT. He presents in your office with a cc of intermittent muscle spams, muscle weakness, and difficulty articulating words. The patient reports that the symptoms began about a year ago and have gradually gotten worse. What is the condition?

Answer 52

ALS