Task 9 Flashcards

1
Q

In a US sample, how many percent of individuals qualify as “heavy drinkers” averaging 2 or more drinks per day?

A

7%

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2
Q

What is a demographic factor that substantially effects the prevalence of alcohol use?

A

Ethnicity

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3
Q

Name some examples of what kind of health implications long-term heavy alcohol use could have?

A

Cancer, Liver problems, cardiac diseases, dementia, neurocognitive diseases (dementia etc.)

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4
Q

Which kind of mental disorders are bidirectionally comorbid with substance use disorder?

A

Anxiety and Mood disorders

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5
Q

Which structures are commonly said to be involved in the “pleasure pathway”?

A

VTA -> NAc -> (P)FC

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6
Q

Roughly, why are some drugs so addictive?

A

They manipulate our dopamine levels, which leads to a strong craving of the drug.

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7
Q

How can we biologically explain tolerance?

A

Psychoactive substances cause the brain to reduce dopamine production and the receptors become less sensitive. Thus, more of the drug is needed, to achieve the same level of dopamine release.

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8
Q

Why do people overdose when taking drugs in unfamiliar environments?

A

Because stimuli experienced in association with the drug intake become conditioned stimuli and increase an individuals tolerance when present. When the stimuli are not present however, the drug’s effect might be much stronger than anticipated.

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9
Q

Social learning is a factor which could cause substance use disorders. Why might this also partially explain the gender difference when it comes to the prevalence of alcohol abuse?

A

On a societal level, drinking has historically been a more male-dominated activity. Boys typically tend to see their fathers as role models, and thus, heavy drinking in men might propagate itself into a vicious circle over the generations.

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10
Q

What is a personality trait, which puts people at a higher statistical risk of developing a substance use disorder?

A

Sensation-seeking

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11
Q

When facing difficult life events, people might turn to drugs as a form of …

A

maladaptive coping strategy

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12
Q

How can a person’s attitude influence the effect a drug has on them?

A

People’s expectations of the effects of a drug can predict what is going to happen.
-> People who expect marijuana to make them relaxed may experience relaxation, whereas people who are frightened of disinhibition may experience anxiety.

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13
Q

Which gender tends to be more influenced by their peers when it comes to developing a SUD (Substance use disorder)?

A

Males

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14
Q

What are some sociocultural factors that are affect the prevalence of SUD?

A
  • Low SES
  • Being in a stressful life situation like an abusive relationship etc.
  • Religion (some religions condemn alcohol and other drugs more than others)
  • Gender (more acceptable and popular among men)
  • Family
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15
Q

What is one of the strategies in biologically treating addiction?

A

Example: Giving medication, which has a similar effect as the drug and then slowly decrease dosage of the medication, all while abstaining from using the actual drug.

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16
Q

What is the effect of antagonistic drugs and what is a problem of antagonistic drug treatment?

A

They block or change the effect another drug has in a way, that reduces the patient’s desire to take it.
Problem: Withdrawal effects and side-effects -> Generally criticized treatment

17
Q

Name an example for an antagonistic Drug.

A

Disulfiram: Makes alcohol feel like shit

18
Q

What are the sub-goals of most psychosocial treatments?

A
  • Motivate the patient to want to quit
  • teach them coping strategies to replace the drug
  • change reinforcers of taking the drug (social circle etc.)
  • enhance support from non-using peers and family
19
Q

Which kinds of conditioning can be used in treatment of addiction?

A

Aversive and Operant

20
Q

What are three key aspects of cognitive treatment?

A
  • Challenging positive thoughts about the drug and their outcomes
  • Teaching ways to handle situations that were formerly associated with taking the substance
  • Learning to withstand social pressure
21
Q

What is a treatment combination, that typically leads to good results?

A

Psychosocial Therapy + Naltrexone Treatment

22
Q

Who is a popular proponent of the choice model of addiction (He wrote a book in 2009)?

A

Hayman

23
Q

What is a central argument supporting the choice model of addiction?

A
  • Quitting a drug is based on cognitive decisions. This is not the case with diseases.
24
Q

How does the choice model of addiction explain the decision to take a drug?

A

Addiction is when immediate reward (local) trumps over long-term gains (global).

25
Q

In his article, Lewis summarized his view on the disease-choice debate in one sentence. Paraphrase his opinion.

A

Actual quote: “Addiction is a biological as well as psychological condition, based on an unusually strong connection between hedonic experience and neural restructuring, facilitated by dopamine’s pull for the immediate.”
Explanation:
-> Biological explanation and choice explanation aren’t mutually exclusive
-> Drugs represent a great craving (not reward), thus decisions are biologically influenced, which adds the disease component to the choice model
-> Craving and reward salience is on a neurological level dramatically increased moments before intake of a drug, which basically makes the addict unable to consider long-term gains.
-> Addiction leaves behind a structural and endocrine change in the brain, which reduces the addicts capability of making reflected decision like a healthy individual.

26
Q

What is a phylogenetic perspective, that supports the disease model of addiction?

A

Drugs affect dopaminergic decision processes, which are phylogenetically far older and deeply rooted in the brain, than the process of making a reflected decision.

27
Q

According to a Dual-process model of addiction, there are dysfunctions in two distinct systems. Describe this.

A
  • under-activation of the reflective system

- over-activation of the affective-automatic system

28
Q

What is the Continuum Hypothesis?

A

“There are qualitatively similar deficits across different alcohol-related disorders, and they differ quantitatively along a continuum.”

29
Q

How did studies show that in binge-drinking disordered individuals, the reflective system is impaired?

A

They found higher latency and lowered peak size in ERP recordings during cognitive tasks.

30
Q

In Lannoy et al’s article, they give direction in which future research should be done. What are three main aspects of binge-drinking, that should be explored?

A
  • Affective-Automatic System
  • Interactions between systems
  • Development of the imbalance between the systems across stages of alcohol-dependence
31
Q

What are two kinds of drugs which belong to the class of depressants?

A
  • Alcohol

- Benzodiazepines (Benzos)

32
Q

There are three stages of withdrawal symptoms of alcohol. In which stage do convulsive seizures appear?

A

Stage 2

33
Q

What are four stimulant drugs?

A

Cocaine, Amphetamines, Ritalin, Nicotine

34
Q

What are the three most popular Opioids?

A

Heroin, Codeine, Morphine

35
Q

Name three Hallucinogens.

A

PCP, LSD, Cannabis