Targets for drug action L10

Question 1

Drus interact with 3 things what are they?

Answer 1

Receptors
Enzyme (Enhance or inhibit it)
Ion channel

Question 2

A specialized target macromolecules present on the cell surface or within the cell

Answer 2

Receptors

Question 3

Drugs act as …… & receptors act as ………

Answer 3

signals
signal detectors

Question 4

a naturally occurring molecule or a drug that binds to a site on a receptor protein and activates it

Answer 4

Agonist

Question 5

“Second messenger” effector molecules function is to?

Answer 5

cascade of events
translates agonist binding into a cellular response

Question 6

Name the Types of receptors?

Answer 6

ligand-gated ion channels
Enzyme-linked receptors
Intracellular receptors

Question 7

The channel is closed When receptor is activated
the channel opens

Answer 7

Ligand-gated ion channels

Question 8

cholinergic nicotinic receptor is an example for which receptor?

Answer 8

ligand-gated ion channels

Question 9

When activated, receptors undergo conformational changes resulting in increased cytosolic enzyme activity

Answer 9

Enzyme-linked receptors

Question 10

insulin receptors is an example for

Answer 10

Enzyme-linked receptors

Question 11

nuclear steroid receptors is an example for

Answer 11

Intracellular receptors

Question 12

drug must diffuse into the cell to interact with the receptor The activated ligand–receptor complex then
translocates to the nucleus

Answer 12

Intracellular receptors