24/25 Flashcards

1
Q

Amphetamine effects

A

Central nervous system stimulant
1. increase release of catecholamines from nerve terminals)
2. Inhibit monoamine oxidase (MAO)
3. Inhibit catecholamine reuptake

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2
Q

an indirect-acting adrenergic drugs

A

Amphetamine
Cocaine

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3
Q

Therapeutic uses of amphetamine

A
  1. Attention deficit hyperactivity disorder (ADHD)
  2. Narcolepsy
  3. Appetite suppression
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4
Q

Methylphenidate

A

is a central nervous system (CNS) stimulant medication used to treat
(ADHD) and, to a lesser extent, narcolepsy

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5
Q

What is a primary medication for ADHD

A

Methylphenidate

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6
Q

Phentermine IS used to treat

A

obesity

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7
Q

Amphetamine Adverse effects

A
  1. Central nervous system effects: (Addiction, insomnia, irritability, tremor, and hyperactive reflexes, weakness, confusion, dizziness , delirium, panic states) amphetamine psychosis, schizophrenia 2. Cardiovascular effects: palpitations, cardiac arrhythmias, hypertension and
    anginal pain. 3. Gastrointestinal system effects: anorexia, nausea, vomiting, abdominal
    cramps, and diarrhea.
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8
Q

Amphetamine Contraindications

A
  1. Patients with hypertension, cardiovascular disease,
    hyperthyroidism, glaucoma, or a history of drug abuse
  2. Patients taking MAO inhibitors should not be treated with amphetamine.
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9
Q

Cocaine mechanism is indirect by

A

block the cellular uptake of norepinephrine into the
adrenergic neuron

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10
Q

Tyramine is found in

A

fermented foods, (such as aged cheese)

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11
Q

mixed-action non-selective adrenergic agents

A

Ephedrine and pseudoephedrine

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12
Q

Ephedrine and pseudoephedrine release what? Stimulates what?

A
  1. They release stored norepinephrine
    from nerve endings
  2. And stimulate both α and β receptors.
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13
Q

Therapeutic uses of Pseudoephedrine:

A

Used to treat nasal and sinus congestion (orally)
Raise bp

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