Targeted AntiCa Drugs

Question 1

CML TK#

Answer 1

I -Imatinib [DOC]
N-Nilotinib
D-Dasatinib

Question 2

Lung Ca TK#

Answer 2

After- Afatinib
E-Erlotinib
C-Ceritinib
G-Geftinib

Question 3

Renal cell Ca TK#

Answer 3

P- Pazopanib
A- Axitinib
S- Sorafenib
S- Sunitinib

Question 4

Hepatic Cell Ca TK#

Answer 4

Sorafenib

Question 5

GIST TK#

Answer 5

S-Sunitinib
I- Imatinib [DOC]
R-Regorafenib (also used for colorectal Carcinoma)

Question 6

Malignant Melanoma TK#

Answer 6

D- Dabrafenib
V- Vemurafenib
T- Trametinib

Question 7

Medullary Ca of thyroid TK#

Answer 7

Vandetanib

Question 8

Protease #

Answer 8

Bortezomib
Carfilzomib
Ixazomib

Used for Multiple Myeloma

Question 9

PARP#

Answer 9

•Olaparib

O -Ovarian carcinoma [Used]
LA
P -Poly
A -ADP
RIB-Ribose Polymerase

Question 10

CDKI

Answer 10

Palbociclib
Acts on CDK-4, CDK 6

PAL -
B -Breast cancer [Used]
0 -Oral
CICLIB-Cyclin dependent Kinase #

Question 11

Monoclonal antibodies

Answer 11

•Cetuximab. -Colorectal Ca
•Panitumumab -Colorectal Ca
•Rituximab -NHL
•Trastuzumab -Used forBreast Ca
(S/E-cardiotoxicity)
•Pertuzumab. - Breast Ca
•Daratumumab -Multiple Myeloma
•Olaratumab. -Soft tissue Sarcoma