T4 L5: Respiration control and ABG's Flashcards
What is an ABG?
An arterial blood gas test
What is an ABG used for?
To test for the acid/base balance and the ventilatory status
Why is an ABG taken from arteries?
Because the results are more accurate than in veins
What is meant by ‘CO2 isn’t an acid but acts like one’?
When C02 levels go up, the pH goes down because H2CO3 (carbonic acid) is produced
What happens to blood pH when CO2 elimination is insufficient?
[H+] increases so pH decreases
What is the carbonic anhydrase equation?
C02 + H2O = H2CO3 = HCO3- + H+
What is respiratory acidosis?
The build up/ retention of CO2
What are fixed/ non-volatile acids?
Those that can’t be eliminated by exhalation
How does the body get fixed/ non-volatile acids?
By the oxidation of dietary substrates
How are fixed acids eliminated from the body?
Via the kidneys or the liver. They end up in urine
What are the 3 most important buffers in the body?
Carbonate, proteins circulating in the blood that have histamine residue Eg. Albumin, and phosphates
What ion balances out H+?
Cl-
How do we measure the abnormal accumulation of fixed acids?
Through the anion gap
What is the anion gap?
The gap between the uncounted cations an anions. It helps to measure the acid/base balance
What are those most abundant cations in the blood which are used for the anion gap test?
Na+ and K+ plus some uncounted cations
What are the most abundant anions in the blood which are used for the anion gap test?
Cl- and bicarbonate plus some uncounted anions