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ESA1-4 revision sessions > T2DM > Flashcards

T2DM Flashcards

1
Q

types of T2DM medication

A

Biguanides–> metformin

Sulphonyureas–> Glicazide

Glitazones (thiazolidinediones)–> Pioglitazone

Gliflozins (SGLT2 inhibitors)–> Canaflozin

Gliptins (DDP-4 inhibitors) —> Saxagliptin

GLP receptor analogues –> Exenatide

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2
Q

name a sulphonylureas

A

glicazide

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3
Q

name a biguanide

A

metformin

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4
Q

name a glitazone (thiazolindinediones)

A

pioglizatone

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5
Q

name a gliptin (DPP-4 inhibitor)

A

saxagliptin

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6
Q

name a gliflozin (SGLT-2 inhibitor)

A

canaflozin

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7
Q
A
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8
Q

name a GLP-1 receptor agonist (incretin mimic)

A

Exenatide

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9
Q

glicazide MOA

A

stimulating pancreatic insulin secretion

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10
Q

metformin (biguanide) MOA

A

reducing hepatic glucose output by reducing glucoseneogenesis

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11
Q

glitazone MOA

A

enahnced insulin sensitvity and glucose utilisation

–> stimulates ppar-γ which encourages conversion of glucose –> triglycerides

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12
Q

gliptins MOA

A

prevent incretin degradation

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13
Q

incretins promote

A

incretins promote insulin secretion and supress glucagon release

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14
Q

gliflozins

A

reduce glucose reabsorption

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15
Q

incretin mimimics (GLP-1 receptor agonists) MOA

A

increase glucose-dependent synthesis of insulin

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16
Q

how are DM medications admistered

A

all PO bar one which is delivered SC

17
Q

which DM drug is adminsitered subcutaneouly

A

exenatide- glucagon-like peptide 1 receptor agonists (incretin mimetics)

protein so would be digested if given enterally

18
Q

which drugs can cause hypoglycaemia when administered alone

A

glicazide (sulphonylures) and metformin (biguanides)

19
Q

which drugs increase appetite

A

glicazide (sulphonylureas)

20
Q

which drugs suppress appetite

A

Glitpins and biguandides

21
Q

which drug increases satiety

A

GLP receptor agonists (exenatide)

22
Q

which drug helps decrease weight

A

gliflozins (SGLT-2) inhibitors

ESA1-4 revision sessions (17 decks)

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