T Cell ALL Flashcards

1
Q

What is the mutation?

A

Oncogenic translocation to T cell Receptor region on chromosome 14

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2
Q

Who gets it?

A

Kids 25% of pediatric leukemia

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3
Q

Presentation>

A

Thymis enlargemtent, Lymph mass, splenomegally

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4
Q

Immunophenotype?

A

CD3, CD5, TdT

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