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Leukemias of the lymphoid lineage > Haiiry Cell Leukemia > Flashcards

Haiiry Cell Leukemia Flashcards

1
Q

What is the mutation

A

BRAF V600F

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2
Q

What is surprising about it?

A

No lymphadenopathy

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3
Q

Key diagnosis?

A

Resistant to TRAP (Tartrate-resistant acid phosphatase

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4
Q

Presentation>

A

Splenomegaly, Thrombocytopenia, DRY BONE MARROW

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5
Q

WHo gets it?

A

Middle aged men

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6
Q

Immunophenotype?

A

CD19, CD20

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7
Q

Treatment?

A

Interferon, Cladribine, Pentostatin…..easily cured if you catch it.

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8
Q

Pneumonic for cell type and treatment

A

Hairy B ICP

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Leukemias of the lymphoid lineage (5 decks)

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