systemic risk factors Flashcards

1
Q

Give examples of individual risk factors

A
  1. Smoking
  2. Stress
  3. Diabetes
  4. Genetic factors
  5. Osteoporosis
  6. Alcohol
  7. Dietary calcium
  8. Obesity
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2
Q

What have cross sectional and longitudinal studies show smokers have?

A

Smokers have:
1. Greater bone loss and attachment loss
2. Increased numbers of deeper pockets
Than non smoker with similar plaque levels

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3
Q

Describe the clinical appearance of periodontitis in a smoker

A
  1. Fibrotic tight gingiva
  2. Rolled margins
  3. Less gingival redness and bleeding
  4. More severe and widespread disease than the same aged non smoker
  5. Anterior maxilla palate worst affected
  6. Nicotine staining and calculus
  7. Anterior recession and open embrasures
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4
Q

Describe features of necrotising gingivitis

A
  1. Painful interdental necrosis
  2. Bleeding gingiva
  3. Necrotic ulcers affecting interdental papillae
  4. Punched out appearance
  5. Painful ulcers covered in grey slough
  6. Possible halitosis
  7. Possible lymph nodes involvement
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5
Q

What effect does nicotine have on neutrophils?

A
  1. Inhibits phagocytosis of neutrophil
    1. Reduction in chemotaxis and migration of oral neutrophils exposed to nicotine
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6
Q

How does nicotine effect fibroblasts

A

Affects fibroblast function and penetrates the oral epithelium

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7
Q

How does nicotine aft our body immunological responses

A
  1. Inhibits phagocytes of neutrophil
  2. Reduces chemotaxis and migration of oral neutrophils
  3. Affects fibroblast function
  4. Reduces antibody production
  5. Alters peripheral blood immune regulatory T cells subset ratios
  6. Reduces bone mineralisation
  7. Is cytotoxic
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8
Q

How does nicotine effect the blood

A
  1. Has adverse effect in the micro circulation, gingival circulation and blood flow
  2. Possibly could cause vasoconstriction of gingival capillaries
  3. Chronic hypoxia of periodontal tissues
  4. There’s a higher proportion of small blood vessels in smokers
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9
Q

What does evidence suffer about smokers inflammatory response

A

Smokers with periodontal disease have the associated vascularity so worn bleed as much as a non smoker

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10
Q

Overall what would see clinically in a smoker suffering from periodontitis

A
  1. Less gingival redness
  2. Less bleeding on probing
  3. Fewer vessels clinically and histologically
  4. Healing response may be affected by impairment of revascularisation
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11
Q

What are the clinical characteristics of a smoker with periodontal disease

A
  1. Relatively the periodontal disease starts earlier
  2. More rapid disease progression
  3. Poorer response to non surgical therapy
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12
Q

How is the treatment of periodontal disease affected by a patients smoking status

A
  1. Smokers repose less well to periodontal therapy
  2. Over 90% of refractory patients have been found to be smokers
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13
Q

What should you advice to patients who smoke?

A

Advice them of the adverse effects of smoking on their oral and periodontal health (+general health)
You should explain poorer response to periodontal therapy

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14
Q

How can stress affect the oral environment?

A

Known to affect host immune response making an individual more susceptible to periodontal disease

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15
Q

What is the link between stress and periodontal disease?

A

Correlation between periodontal disease and stress
Traumatic events, increases the risk of periodontal disease but individuals with increased ability to cope with a stressful stimulus had reduced impact on the progression of periodontal disease

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16
Q

What is diabetes mellitus characterised by

A

Chronic hyperglycaemia from insulin deficiency or impaired utilisation of insulin

17
Q

What problems can poorly controlled diabetes lead to in dentistry?

A

Periodontal disease as patients have more attachment and bone loss

18
Q

What increases the severity of periodontal disease in diabetes

A

Increased age and increases with diabetes duration

19
Q

What links diabetes mellitus and periodontitis

A

Inflammation

20
Q

What does periodontal disease induce

A

Systemic inflammatory response

21
Q

What does an increased inflammatory response lead to

A

Increase levels of acute phase proteins and pro pro inflammatory cytokines

22
Q

What has research suggested periodontal disease can have an effect on in regards to diabetes?

A

Diabetes control complications and incidences

23
Q

Name some other systemic diseases that affect periodontal disease

A
  1. Cardiovascular disease
  2. Ischaemic heart disease
  3. Cerebrovascular disease
  4. Chronic obstructive pulmonary disease
24
Q

Give some other risk factors of periodontal disease

A

Osteoporosis
Dietary Calcium
Vitamin D
Obesity

25
Q

What is osteoporosis

A

A condition where bone mineral density is reduced leading to an increase in factor risk