Systemic lupus erythematosus Flashcards

1
Q

Women are (more/less)——-commonly affected by systemic lupus erythematosus than men.

A

more

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2
Q

———–endocarditis is a complication of systemic lupus erythematosus that involves sterile, wart-like vegetations on both sides of cardiac valves.

A

Libman-Sacks

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3
Q

The antibodies indicative of systemic lupus erythematosus are —– , ——-, and —————-.

A

anti-dsDNA
anti-Smith
anti-nuclear antibody

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4
Q

Anti-Smith antibodies are (sensitive/specific) —– for systemic lupus erythematosus.

A

specific

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5
Q

Lupus-associated ——— antibody syndrome results in arterial and venous thrombosis.

A

antiphospholipid antibody

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6
Q

——— antibodies may cause a false positive test for syphilis in antiphospholipid antibody syndrome associated with systemic lupus erythematosus.

A

Anti-cardiolipin

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7
Q

——— antibodies are indicative of a poor renal prognosis in systemic lupus erythematosus.

A

Anti-dsDNA

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8
Q

Anti-nuclear antibodies are (sensitive/specific)———for systemic lupus erythematosus.

A

sensitive

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9
Q

Common causes of death in patients with systemic lupus erythematosus are cardiovascular disease, infections, and end-stage ———disease.

A

end-stage renal disease.

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10
Q

Treatment for lupus-associated antiphospholipid antibody syndrome requires lifelong ———-.

A

anticoagulation

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11
Q

The —— antibodies implicated in systemic lupus erythematosus are directed against small ribonucleoproteins or snRNPs.

A

anti-Smith

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12
Q

Complement levels are (increased/decreased/unchanged)——— in systemic lupus erythematosus due to immune complex formation.

A

decreased

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13
Q

(Warm/Cold) ——- autoimmune hemolytic anemia is a type of chronic anemia common in systemic lupus erythematosus.

A

Warm

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14
Q

———is a systemic autoimmune disorder associated with membranous nephropathy.

A

Systemic lupus erythematosus

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15
Q

——— and ——– rashes are common clinical features of systemic lupus erythematosus.

A

Discoid and malar’butterfly’ rashes are common clinical features of systemic lupus erythematosus.

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16
Q

Diagnosis of systemic lupus erythematosus requires———of the eleven diagnostic criteria.

A

four of the eleven diagnostic criteria.