Rheumatoid arthritis

Question 1

— is an autoantibody found in 80% of rheumatoid arthritis cases.

Answer 1

Rheumatoid factor is an autoantibody found in 80% of rheumatoid arthritis cases.

Question 2

——-peptide antibody is an antibody more specific to rheumatoid arthritis than rheumatoid factor.

Answer 2

Anti-cyclic citrullinated peptide antibody is an antibody more specific to rheumatoid arthritis than rheumatoid factor.

Question 3

Rheumatoid arthritis is associated with HLA- —– .

Answer 3

Rheumatoid arthritis is associated with HLA-DR4.

There are 4 walls in a rheum.

Question 4

Radiographs of joints affected by rheumatoid arthritis may reveal joint-space narrowing, cartilage loss, and ——–.

Answer 4

Radiographs of joints affected by rheumatoid arthritis may reveal joint-space narrowing, cartilage loss, and osteopenia.

Question 5

The etiology of rheumatoid arthritis involves autoimmune destruction of (cartilaginous/synovial)——joints mediated by cytokines.

Answer 5

The etiology of rheumatoid arthritis involves autoimmune destruction of (cartilaginous/synovial) synovial joints mediated by cytokines.

Question 6

——–arthritis is a joint disorder characterized by morning joint stiffness that lasts for at least one hour and improves with movement.

Answer 6

Rheumatoid arthritis is a joint disorder characterized by morning joint stiffness that lasts for at least one hour and improves with movement.

Question 7

The joint disorder ——arthritis is treated with tumor necrosis factor-alpha inhibitors like infliximab.

Answer 7

The joint disorder rheumatoid arthritis is treated with tumor necrosis factor-alpha inhibitors like infliximab.

Question 8

Rheumatoid arthritis is more common in (men/women) ——-.

Answer 8

Rheumatoid arthritis is more common in (men/women) women.

Question 9

Rheumatoid arthritis involves ——– formation, which leads to cartilage destruction and joint ankylosis.

Answer 9

Rheumatoid arthritis involves pannus formation, which leads to cartilage destruction and joint ankylosis.

Question 10

Subcutaneous rheumatoid ——-are a systemic symptom of rheumatoid arthritis that involve fibrinoid necrosis of subcutaneous tissue.

Answer 10

Subcutaneous rheumatoid nodules are a systemic symptom of rheumatoid arthritis that involve fibrinoid necrosis of subcutaneous tissue.

Question 11

The cellular differential analysis of synovial fluid from a joint affected by rheumatoid arthritis would reveal ≥50% (neutrophils/natural killer cells) ——–.

Answer 11

The cellular differential analysis of synovial fluid from a joint affected by rheumatoid arthritis would reveal ≥50% (neutrophils/natural killer cells) neutrophils.

Question 12

Anti-Ig ——–antibodies are a classic lab finding in rheumatoid arthritis.

Answer 12

Anti-IgG antibodies are a classic lab finding in rheumatoid arthritis.

Question 13

——-is a combination of sulfapyridine and 5-aminosalicylic acid used to treat rheumatoid arthritis.

Answer 13

Sulfasalazine is a combination of sulfapyridine and 5-aminosalicylic acid used to treat rheumatoid arthritis.

Question 14

Bilateral symmetrical joint involvement is associated with——- arthritis.

Answer 14

Bilateral symmetrical joint involvement is associated with rheumatoid arthritis.

Question 15

Analysis of synovial fluid from a joint affected by rheumatoid arthritis would reveal (high/low) ——— protein levels.

Answer 15

Analysis of synovial fluid from a joint affected by rheumatoid arthritis would reveal (high/low) high protein levels.

Question 16

Symmetric “——-“ deformities in the proximal interphalangeal joints are indicative of rheumatoid arthritis.

Answer 16

Symmetric “swan-neck” deformities in the proximal interphalangeal joints are indicative of rheumatoid arthritis.

Question 17

The (proximal/distal)——–interphalangeal finger joints are typically spared in rheumatoid arthritis.

Answer 17

The (proximal/distal) distal interphalangeal finger joints are typically spared in rheumatoid arthritis.