Dermatomyositis Flashcards
Dermatomyositis is an immunologic disease that damages small ——— , which contributes to muscle injury.
Dermatomyositis is an immunologic disease that damages small blood vessels, which contributes to muscle injury.
The three different types of autoantibodies associated with dermatomyositis are ——-, anti-signal recognition particle, and anti-Mi-2.
The three different types of autoantibodies associated with dermatomyositis are anti-Jo-1, anti-signal recognition particle, and anti-Mi-2.
Perimysial inflammation in dermatomyositis may manifest as a ——- rash, a malar rash, or a heliotrope rash.
Perimysial inflammation in dermatomyositis may manifest as a “shawl-and-face” rash, a malar rash, or a heliotrope rash.
A ——–rash of the upper eyelids can be seen in dermatomyositis.
A heliotrope rash of the upper eyelids can be seen in dermatomyositis.
Dermatomyositis is commonly associated with bronchogenic, ovarian and ——– cancer.
Dermatomyositis is commonly associated with bronchogenic, ovarian and breast cancer.
(Proximal/Distal) ———-muscle weakness in dermatomyositis is seen first.
(Proximal/Distal) Proximal muscle weakness in dermatomyositis is seen first.
Muscle biopsy in patients with dermatomyositis reveals ——–.
Muscle biopsy in patients with dermatomyositis reveals inflammation of the perimysium.
——- are red, scalar papules on the knees, elbows, and knuckles that are pathognomonic for dermatomyositis.
Gottron papules are red, scalar papules on the knees, elbows, and knuckles that are pathognomonic for dermatomyositis.
Dermatomyositis puts patients at an (increased/decreased)——— risk for occult malignancy.
Dermatomyositis puts patients at an (increased/decreased) increased risk for occult malignancy.
The (anti-Mi2/anti-Jo1) —— antibodies show a strong association with prominent Gottron papules in dermatomyositis.
The (anti-Mi2/anti-Jo1) anti-Mi2 antibodies show a strong association with prominent Gottron papules in dermatomyositis.
Dermatomyositis is an autoimmune condition involving the muscle and skin, caused by (CD4/CD8) ——– T cells that cause perimysial inflammation and atrophy.
Dermatomyositis is an autoimmune condition involving the muscle and skin, caused by (CD4/CD8) CD4 T cells that cause perimysial inflammation and atrophy.
——- is a medication used in long term therapy of dermatomyositis.
Methotrexate is a medication used in long term therapy of dermatomyositis.
