Systemic Lupus Erythematosus Flashcards
1
Q
SLE
A
A multi system, inflammatory auto immune disorder that affects primarily women of childbearing age
2
Q
SLE Signs/ Symptoms
A
Fever Anorexja Malaise Weight loss Butterfly rash Finger tip lesions Periungual erythema Splinter hemorrhages Alopecia Reynards phenomenon and 20% of patients Joint symptoms often early manifestation Photosensitivity Vasculitis Nephritis Ocular manifestations Pericardial manifestations Pulmonary manifestations Abdominal pains, ileus, peritonitis
3
Q
SLE Lab/Diagnostics 
A
ANA + in 95% of patients
Anti-phospholipid antibodies
Anemia, leukopenia, and thrombocytopenia are often present
4
Q
SLE management
A
For mild symptoms: bedrest, mid afternoon naps, avoidance of fatigue
Sun protection
Use topical glucocorticoid for isolated skin lesions
NSAIDs, hydroxychloroquine, glucocorticoid and other therapies
5
Q
Drugs implicated in lupus leg syndrome
A
Cardiovascular medication‘s Amiodarone Atenolol Bupropion Captopril Tegrotol Thorazine Tizon Lopid Glyburide Gold salt Hydralazine Hydroxy Clore Quinn INH Interferons Lithia Lovastatin Methyldopa Oral contraceptives Macrobid Dilantin PTU Quinidine Rifampin Simvastatin Tetracycline 
