Systemic lupus

Question 1

pathophysiology of lupus

Answer 1

body produces antibodies against the bodies own connective tissue causing a chronic multisystem inflammatory symptoms and labs will indicate this

Question 2

major complication of lupus

Answer 2

multisystem organ failure

Question 3

medications that cause SLE

Answer 3

procainamide, hydralyzine, isoniazid

symptoms subside once medication is discontinued

Question 4

risk factors for SLE

Answer 4

ahes 20-40
AA, asian, NA decent
could be delayed because s/s are similar to aging

Question 5

clinical manifestations of SLE

Answer 5

fatigue 
maliase 
alopecia 
blurred vision 
pleuric pain (systemic) 
anorexia and wt loss 
depression
joint pain/swelling /tenderness can also be caused by medications used 
anemia 
fever- exacerbation 
lymphandenopathy 
Pericarditis 
raynauds 
consistant finding with organ involvement 
morning stiffness
arthraglia 
butterfly rash on the face

Question 6

main sign of exacerbation of SLE

Answer 6

fever

Question 7

Cardiac symptoms SLE

Answer 7

Pericarditis, substernal chest pain, valvular disorders, artherosclerosis

Question 8

renal symptoms SLE

Answer 8

nephritis, can lead to kidney failure monitor GFR/ BUN/ Creatnine

Question 9

CNS involvement of SLE

Answer 9

psychosis, cognitive impairment, seizures, peripheral and cranial neuropathy

Question 10

diagnosis of SLE

Answer 10

test for hep c
elevated ESr
serum C3 and C4 are decreased
panocytopenia

Question 11

dx tests when kidneys are involved in SLEs

Answer 11

bun/creatnine

UA: positive for blood

Question 12

whats pancytopenia?

Answer 12

decrease in all blood counts

Question 13

medications for SLE- Nsaids

Answer 13

NSAIDS- renal function

Monitor for NSAID induced hepatitis

Question 14

nursing considerations with prendisone

Answer 14

taper dosage

monitor for fluid retention, HTN, impaired kidney function

Question 15

nursing considerations with methotrexate and azathioprine

Answer 15

used for immunosupression
ASL/LFT 
can suppress liver, bone marrow
consider panocytopenia
monitor for toxicity

Question 16

nursing considerations with antimalarial medications

Answer 16

hydroxychloroquine used for suppression of synovitis, fever, and fatigue
encourage frequent eye exams because it can cause issues with sight

Question 17

nursing interventions with SLE

Answer 17

avoid uv exposure
mild shampoo avoid harsh hair treatments
use steroid creams for rash
report edema promptly (nephritis)
report infection
avoid sick people and crowds
educate clients who are child bearing of teratogenic effects of medications

Question 18

DAMP AS A RHINO

Answer 18

Discoid rash 
ANA +
Malar Rash 
Photosensitivity 
arthritis 
serositis (plueral, pericardial)
renal involvement 
hematologic abnormality 
immunologic abnormality 
neurological abnormality (seizures and psychosis) 
oral/nasal ulcer

Question 19

cause of death in SLE

Answer 19

renal disease 3-5 years
those who dont die from renal disease die from CVD at younger age
SLE women age 35-44 are 50xs more likely to have MIs