pancreatic cancer Flashcards

1
Q

occurs more frequently in men or women?

A

men

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2
Q

survival rate of pancreatic cancer

A

5%

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3
Q

increased risk with

A
age 
smoking 
chemical or toxin exposure 
certain petroleum 
etoh, high fat and protien, low fiber may increase risk
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4
Q

10-20% of those diagnosed with pancreatic cancer also are having

A

diabetes

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5
Q

why is pancreatic cancer called the “silent disease”?

A

early cancer does not cause symptoms
if tumor blocks the common bile duct then he bile can not pass into the digestive system
they m

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6
Q

if tumor blocks the common bile duct then he bile can not pass into the digestive system

A

pt will become jaundice

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7
Q

pain of pancreatic cancer can

A

develops in upper abdomen then back

be caused when a person lies down or eats

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8
Q

s/s of pancreatic cancer

A

nausea, loss of appetite, weight loss, weakness

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9
Q

clinical manifestations of pancreatic cancer

A

present of pain and jaundice
rapid/progressive wt loss
mid to upper abd pain unrelated to GI function
pain/dysfunction described as boring to mid back pain unrelieved by posture or activity
worse in supine position
pain is relived sitting up and leaning forward
pain is progressive and severe, requires use of opioids for pain relief
disease is progressed (jaundice and pruitis)

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10
Q

assessment of pancreatic cancer

A
appearance of jaundice 
clay colored stools 
dark urine 
dry skin 
fatigue 
dull pain associated w eating 
back pain w nerve plexus
anorexia w early satiety, nausea, flactulance, vomiting, gi bleed  
diabetes
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11
Q

what can occur w late state pancreatic cancer?

A

ascites

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12
Q

whats gonna be elevated w pancreatic cancer?

A

amylase, lipase, alkaline phosphate, bilirubin, CEA, DU-pan 2

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13
Q

Du-pan2 test

A

non specific for carcinomas

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14
Q

dx studies

A

angiogram
ct
mri
ERCP (special xray of bile duct)

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15
Q

Percutaneous trans-hepatic biliary drain

A

aspiration of fluid, also reveals malignant cells and elevated amylase

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16
Q

types of tumors

A

head of pancreas- bile duct blockage

islet tumors- hyperinsulinemia

17
Q

pre op whipple

A
high protien diet 
hydration 
correct pt w vit k 
tx anemia 
TPN 
biliary shunt may be placed to decrease jaundice
18
Q

hyperinsulinism

A

caused by over production of insulin islet cells
s/s: decreased bgt
trx: po/iv glucose
needs to have a surgical excision of hyperplasia

19
Q

ulcerogenic tumors

A

zollinger-ellison syndrome: islets hypersecrete ulcers gastric acid and cause ulcers to form
surgical intervention is needed

20
Q

use of radiation with pancreatic cancer

A

pallative reasons- decrease tumors and decrease pain

does not improve the survival rates

21
Q

survival rate of a non resectable pancreatic tumoe

A

6 months

22
Q

surgical interventions for a pancreatic tumor stage I or II

A

total pancreatectomy

whipple

23
Q

nis for post pancreas surgeries

A

tpn
monitor BG
nutritional support
enteral feeds/ tpn

24
Q

post op whipple

A
ng suction 
tpn to rest gut 
pitting edema 
volume needs to be replaced 
monitor bgts 
h/h 
subacute rehab is most likely needed
25
Q

ng drainage post op whipple

A

should be serosanguinous not colorless or bile tinged or frank blood

26
Q

why is a thrombophlebitis likely after a tumor resection

A

increased levels of thromboplastic factors in the blood and necrotic properties results in bloods hypercoagulated state
(also due to bed rest)