Systemic Flashcards

1
Q

Arthropod borne diseases

A
  1. Leishmaniasis (sandfly)
  2. Plasmodium (anopheles)
  3. Chagas (reduviid bug)
  4. Lyme disease (ixodes tick)
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2
Q

Live vaccines

A

» MM! Really Vivacious PAIRS of vaccines «

  1. MMR (only vaccine given to🤰🏻)
  2. VZV
  3. Polio (Sabin, PO)
  4. Adenovirus
  5. Influenza (intranasal)
  6. Rotavirus
  7. Small pox
  8. Yellow fever
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3
Q

Killed vaccines

A

» Always RIP «

  1. Hep A
  2. Rabies
  3. Influenza (intramuscular)
  4. Polio (inactivated)
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4
Q

DDx meningitis / meningoenceph

A
  1. Replication w/in birds : West Nile virus - CSF: lymphocytic pleiocytosis
  2. Bird feces: Cryptococcal - IC pts
  3. # MCC acute meningitis: H.inf + S.pneumo - inc neutrophil count
  4. Sporadic encephalitis: HSV - inc erythrocytes + lymphocytic pleocytosis
  5. Aseptic meningitis: Coxsackie
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5
Q

AIDS-defining illnesses

A

CD4 <200

  1. Candida
  2. Cervical ca
  3. Coccidioides
  4. Cryptococcal meningitis
  5. Cryptosporidium
  6. CMV
  7. Histoplasmosis
  8. Kaposi sarcoma
  9. Burkitt lymphoma
  10. Disseminated Tb
  11. Mycobacterium avium
  12. PCP
  13. PML
  14. Toxoplasmosis
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6
Q

Subunit vaccines

A

» B-UNIT Vaccines «

  1. HBV
  2. pneUmococcus
  3. N.meningitidis
  4. H.Influenza B
  5. DTP
  6. HPV
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7
Q

Growth restriction, hearing loss, cloudy cornea w meningoencephalitis in neonates?

A

Congenital rubella

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8
Q

Unpasteurized milk in🤰🏻

A

Listeria

Chorioamnionitis
Tumbling motility

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9
Q

Mosquito bites in 🤰🏻

A

Zika (flavivirus)

Microcephaly, ocular defects, hearing loss, growth restriction

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10
Q

Congenital retinal lesions, hydrocephalus, jaundice, HSM,

A

Toxoplasma

Raw meat in 🤰🏻

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11
Q

Abx resistance

Penicillin:

Vancomycin:

Quinolone:

Aminoglycosides:

Tetracyclines:

Rifamycin:

A

Penicillin: b-lactam, porins

Vancomycin: peptidoglycan cell wall (Bact replaced w D-lac)

Quinolone: DNA gyrase

Aminoglycosides: methylation of Aminog-binding ribosomal protein, porin proteins

Tetracyclines: inactivated enzymes

Rifamycin: RNA polymerase

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12
Q

Steven Johnson Syndrome seen w which organisms?

A
  1. M.pneumonia
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13
Q

Bugs causing food borne illnesses:

Uncooked meat:

Reheated meat:

Deli, soft cheese:

Poultry, meat, eggs:

Meat, mayonnaisem

Raw/ undercooked sea food:

A

Uncooked meat: E.coli, Toxoplasma

Reheated meat: B.cereus

Deli, soft cheese: Listeria

Poultry, meat, eggs: Salmonella

Meat, mayonnaise: S.aureus

Raw/ undercooked sea food: Vibro

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14
Q

Organisms causing inc cAMP?

A
  1. B.pertussis
  2. ETEC
  3. C.jejuni
  4. V.cholera
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15
Q

Nosocomial infections from-

Contaminated water/ shellfish:

Rusty nails:

Decubitus/ surgical wounds:

IV catheters:

Urinary catheters:

Water aerosol:

Open wounds:

A

Contaminated water/ shellfish: V.vulnificans

Rusty nails: C.tetani

Decubitus/ surgical wounds: S.aureus

IV catheters: S.aureus, S.epidermidis

Urinary catheters: Proteus, E.coli, Klebsiella

Water aerosol: Legionella

Open wounds: C.perf

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16
Q

MCC UTIs

A
  1. E.coli
  2. S.saprophyticus
  3. Klebsiella
  4. Serratia, Enterococcus, Proteus, Pseudomonas

Dx:
+ leukocyte esterase = WBC
+ Nitrite = gram -ve: E.coli
+ Urease = Proteus, Klebsiella, S.saprophyticus

17
Q

MRI Toxoplasma vs CMV

A

Toxoplasma: intracranial calcifications

CMV: PERIVENTRICULAR calcifications

Common Sx: chorioretinitis, blueberry muffin rash

18
Q

Type IIl secretion system seen in?

A
YEPS
Yersinia
E.coli
Pseudomonas 
Shigella, Salmonella 

Inject proteins directly into host w/out invoking an immune response

19
Q

Acute bacterial prostatitis by?

A

E.coli
Proteus
Klebsiella
Pseudomonas

20
Q

Necrotizing fasciitis seen w?

A

V.vilnificans

21
Q

Erythema marginatum seen w?

A

Un Tx Strep pharyngitis

22
Q

Abx against pseudomonas

A

» F CAMP «

  1. Fluroquinolones
  2. Cephalosporin (3,4). Carbapenems
  3. Aminoglycosides: Amikacin, Gentamycin
  4. Monobactams: Aztreonam
  5. Penicillin: Ticarcillin, Piperacillin
23
Q

Endocarditis DDx

N heart valves:

IV drug users:

Hx dental procedure:

A

N heart valves: Strep gallolyticus/ bovis

IV drug users: S.aureus

Hx dental procedure: Viridans

24
Q

Otitis externa

A

Pseudomonas

25
Q

Otitis media

A

H.influenza