Mycology

Question 1

Subq nodules spreading along lymphatics

Answer 1

Sporothrix

Bx: granuloma w/ histiocytes, multi nucleated giant cells + neutroph + plasma cells

Question 2

Mucicarmine stain

Answer 2

Cryptococcus

Methamine silver stain

Question 3

Round yeast w thick polysaccharide capsule (clear areas), narrow-based buds

Answer 3

Cryptococcus

Question 4

Silver stain w septate hyphae w/out any organisms

Answer 4

Aspergillus

Question 5

Round yeast w broad based bud

Answer 5

Blastomyces

Question 6

Budding yeast w pseudo-hyphae and germ tubes

Answer 6

Candida

Question 7

Large, irreg, thick walled spherules w endospored

Answer 7

Coccidioides

Question 8

Small intracellular ovoid budding yeast

Answer 8

Histoplasma

Question 9

Broad hyphae w irreg branching n rare septations

Answer 9

Rhizopus

Question 10

Crescent, crushed ping-pong ball or circular ring around clear center on methamine silver stain

Answer 10

P.jirovecii

Question 11

Which fungi clogs the arachnoid villi?

Answer 11

Cryptococcus

• AIDS defining

Question 12

Defence against local candida infections mediated by?

Answer 12

MCC candidiasis in HIV pts

T-cells prevent superficial candida (oral/ cutaneous / mucous membranes)

Question 13

Defense against systemic candida infections mediated by?

Answer 13

Neutrophils prevent hematogenous spread (candidemia, endocarditis)