Syphilis Flashcards

1
Q

What type of infection is syphilis?

A

Sexually transmitted infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the main organism that causes syphilis?

A

Treponema pallidum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What type of organism is Treponema pallidum?

A

Spirochaete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the intubation period of syphilis?

A

9-90 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How is syphilis characterised?

A

By primary, secondary and tertiary stages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does syphilis present in the primary stage?

A

Chancre - painless ulcer at the site of sexual contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is chancre?

A

Painless ulcer at the site of sexual contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

When does the secondary stage of syphilis tend to occur?

A

6-10 weeks after primary infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does the secondary stage of syphilis tend to present?

A
  • rash on trunk, palms and soles
  • buccal ‘snail track’ ulcers
  • patchy alopecia
  • condylomata lata
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are condylomata lata?

A

Painless, warty lesions on the genitalia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is early latent syphilis?

A

No symptoms but less than 2 years since caught

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is late latent syphilis?

A

No symptoms but more than 2 years since caught

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How does the tertiary stage of syphilis present?

A
  • Neurological
  • Cardiovascular
  • Gummatous – skin lesions
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Is the tertiary stage of syphilis common?

A

No- rare

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How is syphilis diagnosed?

A
  • Clinical signs
  • Serology
  • PCR on sample from an ulcer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What would you look for in serology to diagnosed syphilis?

A

TP IgGEIA, TPPA and RPR

17
Q

What is the first line management of syphilis?

A

Intramuscular benzathine penicillin

18
Q

What is an alternative for the management of syphilis?

A

Doxycycline

19
Q

What are possible complications of syphilis?

A
  • Neurosyphilis – cranial nerve palsies are commonest
  • Cardiac or aortal involvement
  • Congenital syphilis