Synthesis Flashcards
1
Q
Carbonyl -> hydroxynitrile
A
Cyanide ion
NaCN +H2SO4 ->HCN
reflux, alkaline solution
Nucleophilic addition
2
Q
Haloalkane -> nitrile
A
Cyanide ion
KCN
Reflux
Nucleophilic substitution
3
Q
Benzene alkylation
A
Haloalkane + AlCl3 catalyst
room temp, dry inert solvent
electrophilic substitution
4
Q
Benzene acylation
A
Acyl chloride + AlCl3 catalyst
reflux, 50’C, dry inert solvent
electrophilic substitution
5
Q
product of acylation of benzene
A
Phenylketone
6
Q
Reduction of nitriles
A
nitrile +2H2 -> amine
Ni catalyst
7
Q
Acid hydrolysis of nitrile
A
nitrile + 2H2O + HCl -> carboxylic acid + NH4Cl
HCl is dilute/aqueous