Symmetry Flashcards

1
Q

What are 3 types of point group symmetry?

A
  1. Cyclic (C) symmetry
  2. Dihedral (D) symmetry
  3. Polyhedral symmetry (tedrahedral, octahedral, icosahedral)
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2
Q

Hemagglutinin

A

C3 symmetry

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3
Q

GroES (the cap of a protein folding machine)

A

C7 symmetry

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4
Q

GroEL (the body of a protein folding machine)

A

D7 symmetry

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5
Q

Pyruvate dehydrogenase

A

Octahedral symmetry

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6
Q

Tetrahedral symmetry

A

if there is one subunit type, then a complex contains 12 subunits

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7
Q

Octahedral symmetry

A

if there is one subunit type, then a complex contains 24 subunits

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8
Q

Icosahedral symmetry

A

if there is one subunit type, then a complex contains 60 subunits

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9
Q

___ symmetry yields fibers

A

Helical (actin fibers)

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10
Q

___ is the most abundant cytosolic protein in eukaryotic cells

A

Actin

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11
Q

____ binds ATP which it can hydrolyze. It can also bind calcium.

A

G-actin

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12
Q

Tobacco mosaic virus (TMV) adapts _____ symmetry

A

helical

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13
Q

What is the symmetry of the B-pentamer of cholera toxin and enterotoxin?

A

C5 cyclic symmetry

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14
Q

Protein Disulfide Isomerase (PDI) starts in the ____ form and ends in the ____ form when it is helping form a proper disulfide bond when the disulfides are wrongly connected.

A

reduced, reduced

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15
Q

Protein Disulfide Isomerase (PDI) starts in the ____ form and ends in the ____ form when it is helping form a proper disulfide bond when the disulfides are not yet formed.

A

oxidized, reduced

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16
Q

What is known about the GroEL/GroES complex?

A
  • it binds improperly folded globular proteins

- it uses ATP to induce the protein to fold properly

17
Q

True or false. There is one GroES ring, and 2 GroEL rings in the GroES/GroEL system

A

True

18
Q

What are some examples of diseases causing by protein misfolding?

A

Alzheimer’s disease

Mad Cow disease

19
Q

ATCase

A

D3 symmetry

20
Q

Hemocyanin

A

D3

21
Q

Hemoglobin

A

C2 symmetry and 4 subunits