Surgical Management of Lung Cancer Flashcards
What is the assessment of the patient used to determine?
Staging of the lung cancer
Fitness of the patient
What needs to be determined to stage lung cancer?
T, N and M status
What are common clinical findings in the history for lung cancer?
Pain (especially bone pain)
Headaches or neurological symptoms including personality change
Haematuria (presence of red blood cells in the urine)
What is haematouria?
Presence of red blood cells in the urine
What is presence of red blood cells in the urine called?
Haematuria
What are common clinical findings in the examination with lung cancer?
Recurrent laryngeal nerve palsy
Brachial plexus palsy
Superior vena cava obstruction (SVCO)
Supraclavicular lymph nodes
Soft tissue nodules
Chest wall masses
Pleural/pericardial effusion
Hepatomegaly (enlarged liver)
What is hepatomegaly?
Abnormally enlarged liver
What is abnormally enlarged liver called?
Hepatomegaly
What can chest X-rays be used to determine?
Pleural effusion
Chest wall invasion
Phrenic nerve palsy
Collapsed lobe or lung
What is pleural effusion?
Build of of excessive fluid between the pleura
What is the build up of excessive fluid between the pleura called?
Pleural effusion
What are some tests that are useful for staging cancer other than CT?
MRI
Bone scan
ECHO (echocardiogram)
What does ECHO stand for?
Echocardiogram
What is an echocardiogram (ECHO)?
Ultrasound scan used to look at the heart and nearby blood vessels
What is MRI useful for?
Determine degree of vascular and neurological involvement
What test is best for determining the degree of vascular and neurological involvement?
MRI
What is bone scan useful for?
Test for chest wall invasion and for bony metastasis
What test is best for checking chest wall invasion or bony metastasis?
Bone scan
What is an echocardiogram (ECHO) useful for?
Demonstrate presence or absence of significant pericardial effusion
What test is best for demonstrating the presence or absence of pericardial effusion?
Echocardiogram (ECHO)
What is used for the surgical staging of lung cancer?
Bronchoscopy
Mediastinoscopy
What is the fitness for surgery determined by?
Clinical assessment
What systems are looked at during the clinical assessment to determine if someone is fit for surgery?
Cardiovascular
Respiratory
Psychological
Other
What, in terms of the cardiovascular system, is check when determining fitness for surgery?
Angina
Heart problems
High blood pressure
Diabetes mellitus
Peripheral vascular disease
Smoking
Stroke
Carotid bruits
Heart murmors
What is angina?
Chest pain due to not enough blood flow to the heart
What is chest pain due to not enough blood flow to the heart called?
Angina
What is carotid bruits?
Vascular murmur sound (bruit) heard over the carotid artery
What is a vascular murmur sound heard over the carotid artery called?
Carotid bruits
What is a heart murmur?
Unusual sound heard between heart beats
What is an unusual sound heard between heart beats called?
Heart murmur
What, in terms of the respiratory system, is check when determining fitness for surgery?
Barrel-chested
COPD
Smoking
Asthmatic
On oxygen
Exercise capacity
Previous thoractomy
What is barrel-chested?
Broad deep chest
What is a broad deep chest called?
Barrel-chested
What psychologically is checked when determining fitness for surgery?
Past history of mental illness
Severe anxiety
Social background
Chronic pain problems
What additional things will be checked when determining fitness for surgery?
Pulmonary hypertension
Permanent tracheostomy
Rheutamoid artheritis
Immobile patient
Cirrhosis
What is cirrhosis?
Condition where the liver does not function properly due to long term damage
What is a condition where the liver does not function properly due to long term damage?
Cirrhosis
What is respiratory function testing determined by?
Spirometry
Diffusion studies
Arterial blood gasses on air
V/Q scan
What is cardiac assessment determined by?
Electrocardiogram (ECG)
Echocardiogram (ECHO)
CT scan
Exercise tolerance test (ETT)
Coronary angiogram
What does ETT stand up for?
Exercise tolerance test
In terms of operating, what should you do if you are in doubt?
Do not operate
What is the goal for the surgical treatment of lung cancer?
Curative resection
What firm diagnosis is highly desirably before lung resection?
Malignancy
What are the aims of surgical treatment of lung cancer?
Curative resection
Remove minimal amount of lung tissue
Resection of parietal structure is feasible
What does peri-operative deaths mean?
During operation
What are some reasons for peri-operative deaths?
Acute respiratory distress syndrome (ARDS)
Bronchopneumonia
Myocardial infarction
Pulmonary thromboendarectomy (PTE)
Pneumothorax
Intrathoracic bleeding
What does ARDS stand for?
Acute respiratory distress syndrome
What is acute respiratory distress syndrome (ARDS)?
The lungs cannot provide the bodies vital organs with enough oxygen
What is myocardial infarction?
Heart attack
What is the medical name for a heart attack?
Myocardial infarction
What does PTE stand for?
Pulmonary thromboendarectomy
What is a pulmonary thromboendarectomy (PTE)?
Operation that removes thrombus from pulmonary arteries
What is the operation that removes thrombus from the pulmonary arteries called?
Pulmonary thromboendarectomy (PTE)
What are some non-fatal surgical complications?
Post thoracotomy wound pain
Empyema
Wound infection
Atrial fibrillation
Myocardial infarction
Post-op respiratory insufficiency
Gastroparesis/constipation
What is atrial fibrillation?
Irregular and often abnormally fast heart rate
What is an irregular and often abnormally fast heart rate called?
Atrial fibrillation
What are some common problems with the staging of lung cancer?
Collapse of a lobe or lung makes tumour size difficult to asses
Presence of another (usually small) pulmonary nodule
Retrosternal thyroid
Adrenal nodule
CT head is not routinely performed preop
What is the operative mortality of the most dangerous procedure?
5-10%
What is the operative mortality of a pneumonectomy?
5-10%
What is the operative mortality of a lobectomy?
3-5%
What is the operative mortality of a wedge resection?
2-3%
What is the operative mortality of a open/close thoracotomy?
5%
What is the chance of a second primary within 5 years of the operation?
5%
What is the 5 year survival, post-operatively, of T1/2/3 and N<2?
Between 40-70%
What is the 5 year survical, post operatively, of any N2?
16%