Surgery Cervix Flashcards

1
Q

2nd most frequent cancer among women in the ph

A

cervical ca

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2
Q

t/f cervical ca has poor prognosis

A

true

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3
Q

first necessary cause of human cancer

A

hpv dna in cervical neoplasia

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4
Q

transmission of hpv

A
  • skin to skin genital contact

- ~50% of sexually active women will be infected with oncogenic HPV

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5
Q

most oncogenic hpv types

A

16 and 18, 45 and 31

ph: 16, 18, 45, 51, and 52

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6
Q

natural history of hpv to cancer

A

<30 yo = clear the infection

>30 yo = infection persists, can develop into pre-malignant condition and cervical ca

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7
Q

risk factors for hpv

A
  • parity of more/= 7
  • ocp use
  • smoking
  • early coitus
  • multiple partners
  • early age of 1st full term pregnancy
  • co infections + HIV
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8
Q

signs and symptoms of cervical ca

A
  • vaginal bleeding
  • foul smelling watery, bloody vaginal discharge (late)
  • pelvic pain or pain during intercourse (late)
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9
Q

diagnosis of cervical ca

A
  • speculum exam
  • pelvic exam+ punch biopsy
  • cervical punch biopsy
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10
Q

most common type of cervical ca

A

squaca

  • exophytic type of growth
  • cauliflower like lesions growing outward
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11
Q

what is cervical adenoca

A
  • bulky/barrel shaped cervix (cervix is big and mass inside the os)
  • endophytic (grows inward)
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12
Q

previous method for staging

A

clinical: bimanual exam of the pelvis, including palpation of uterus and ovaries; rectovaginal exam

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13
Q

figo staging of cervical ca

A
  • clinical assessment, imaging, patho findings
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14
Q

stage Ia1 and Ia2

A
  • microscopic
  • maximum depth less/= 5 mm
    Ia1 = = 3 mm
    Ia2 = = 5mm
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15
Q

stage Ib1

A
  • still in cervix
  • palpable and visual
  • > 5 mm depth of stromal invasion, = 2 cm in greatest dimension
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16
Q

stage Ib2 and Ib3

A

STILL IN CERVIX

Ib2: > 2 cm and = 4 cm, can be measured clinically, imaging, or pathology

Ib3: >4 cm

17
Q

IIa1 and IIa2

A
  • upper vagina
    IIa1: = 4 cm
    IIa2: > 4 cm
18
Q

IIb

A
  • with parametrial involvement but not up to the pelvic wall
  • mri > ct
  • IIBr = clinically confined to cervix, but see parametrial involvement in mri
19
Q

stage III

A
IIIa = lower third of vagina, no extension to pelvic wall
IIIb = extension to pelvic wall and/or hydronephrosis or nonfunctioning kidney
IIIc1 = pelvic ln
IIIc2 = paraaortic ln
20
Q

stage IV

A
IVa = growth to adjacent organs
IVb = other parts of the body
21
Q

t/f it is recommended that the method for imaging, pathological technique used, and results should be recorded

A

true

22
Q

t/f when in doubt, assign the higher stage

A

false, lower stage

23
Q

in staging r means __ and p means ___

A
r = staged according to radio
p = staged according to patho
24
Q

indication for concurrent chemo/radio

A
  • all stages, this is the standard of care
25
Q

indication for radical hysterectomy

A
  • early stage disease (IA, IB1, IB2, IIA non bulky)

- total hysterectomy + surgical removal of the left and right parametrium up to the pelvic side wall up to upper vagina

26
Q

management for early stage cervical ca (stage I-IIA)

A

radical hysterectomy + concurrent chemorad/rad

27
Q

management for late stage cervical ca (stage II-IV)

A

duration: 3-4 mos

1st phase:

  • pelvic radiation to decrease lateral tumor size
  • chemo (cisplatin)

2nd phase

  • for central tumor
  • brachy (effective upto stage IIIB)
28
Q

primary prevention for cervical ca

A
  • total abstinence
  • lifetime monogamy
  • delay in onset of sexual intercourse
  • use barrier contraceptives
  • prompt and adequate treatment of stds and cin
  • hpv vaccine
29
Q

secondary prevention for cervical ca

A

papsmear for >/= 21 yo

hpv test for >/= 30 yo