Surgery Cervix Flashcards
2nd most frequent cancer among women in the ph
cervical ca
t/f cervical ca has poor prognosis
true
first necessary cause of human cancer
hpv dna in cervical neoplasia
transmission of hpv
- skin to skin genital contact
- ~50% of sexually active women will be infected with oncogenic HPV
most oncogenic hpv types
16 and 18, 45 and 31
ph: 16, 18, 45, 51, and 52
natural history of hpv to cancer
<30 yo = clear the infection
>30 yo = infection persists, can develop into pre-malignant condition and cervical ca
risk factors for hpv
- parity of more/= 7
- ocp use
- smoking
- early coitus
- multiple partners
- early age of 1st full term pregnancy
- co infections + HIV
signs and symptoms of cervical ca
- vaginal bleeding
- foul smelling watery, bloody vaginal discharge (late)
- pelvic pain or pain during intercourse (late)
diagnosis of cervical ca
- speculum exam
- pelvic exam+ punch biopsy
- cervical punch biopsy
most common type of cervical ca
squaca
- exophytic type of growth
- cauliflower like lesions growing outward
what is cervical adenoca
- bulky/barrel shaped cervix (cervix is big and mass inside the os)
- endophytic (grows inward)
previous method for staging
clinical: bimanual exam of the pelvis, including palpation of uterus and ovaries; rectovaginal exam
figo staging of cervical ca
- clinical assessment, imaging, patho findings
stage Ia1 and Ia2
- microscopic
- maximum depth less/= 5 mm
Ia1 = = 3 mm
Ia2 = = 5mm
stage Ib1
- still in cervix
- palpable and visual
- > 5 mm depth of stromal invasion, = 2 cm in greatest dimension