SURFACE MARKERS ON T, B, and NK CELLS Flashcards
DESCRIP FROM MOTHER NOTES
involved in T CELL ACTIVATION
CD2
FOUND ON ALL T CELLS; associated with T-cell antigen receptor
CD3
identifies t-helper cells; also found on most T REGULATORY CELLS; CO-RECEPTOR FOR MHC CLASS II; RECEPTOR FOR HIV
CD4
positive or negative modulation of T and B cell receptor signaling
CD5
IDENTIFIES CYTOTOXIC T CELLS; co-receptor for MHC CLASS II
CD8
protease; marker for PRE-B CALLA
CD10
low affinity Fc receptor for Antibody; mediates phagocytosis
CD16
Part of B-cell receptor; REGULATES B CELL DEVELOPMENT AND ACTIVATION
CD19
RECEPTOR FOR COMPLEMENT COMPONENT C3d; part of B-cell coreceptor with CD19
CD21
REGULATION OF IgE SYNTHESIS; triggers release of GM-CSF from monocytes
CD23
RECEPTOR FOR IL-2
CD25
adhesion molecules mediating homing to peripheral lymphoid organs
CD44
essential in T and B cell antigen-stimulated activation
CD45R
cell adhesion and signaling (FOR CYTOTOXICITY)
CD56
subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity
CD94