SURFACE MARKERS ON T, B, and NK CELLS Flashcards

DESCRIP FROM MOTHER NOTES

1
Q

involved in T CELL ACTIVATION

A

CD2

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2
Q

FOUND ON ALL T CELLS; associated with T-cell antigen receptor

A

CD3

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3
Q

identifies t-helper cells; also found on most T REGULATORY CELLS; CO-RECEPTOR FOR MHC CLASS II; RECEPTOR FOR HIV

A

CD4

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4
Q

positive or negative modulation of T and B cell receptor signaling

A

CD5

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5
Q

IDENTIFIES CYTOTOXIC T CELLS; co-receptor for MHC CLASS II

A

CD8

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6
Q

protease; marker for PRE-B CALLA

A

CD10

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7
Q

low affinity Fc receptor for Antibody; mediates phagocytosis

A

CD16

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8
Q

Part of B-cell receptor; REGULATES B CELL DEVELOPMENT AND ACTIVATION

A

CD19

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9
Q

RECEPTOR FOR COMPLEMENT COMPONENT C3d; part of B-cell coreceptor with CD19

A

CD21

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10
Q

REGULATION OF IgE SYNTHESIS; triggers release of GM-CSF from monocytes

A

CD23

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11
Q

RECEPTOR FOR IL-2

A

CD25

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12
Q

adhesion molecules mediating homing to peripheral lymphoid organs

A

CD44

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13
Q

essential in T and B cell antigen-stimulated activation

A

CD45R

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14
Q

cell adhesion and signaling (FOR CYTOTOXICITY)

A

CD56

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15
Q

subunit of NKG2-A complex involved in inhibition of NK cell cytotoxicity

A

CD94

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16
Q

markers for NK CELLS

A
  1. CD16
  2. CD56
  3. CD94
17
Q

surface markers for PRO-B CELL

A
  1. CD19
  2. CD 45R
  3. CD43
  4. CD24
  5. C-KIT
18
Q

surface markers for IMMATURE B CELLS

A
  1. CD21
  2. CD40
  3. MHC CLASS II
19
Q

surface markers for MATURE B CELLS

A

IgM, IgD

“pag Brainy ka, mag MD ka”

20
Q

surface marker for ACTIVATED B CELLS

A

CD25

21
Q

surface marker for MATURE T CELL

A

CD4, CD8

22
Q

marker for T REGULATORY CELLS

A

CD4, CD25