ANTIBODY CLASSES Flashcards
MOST ABUNDANT Ab in the BODY
IgA
MOST ABUNDANT Ab in the SERUM
IgG
ratio of IgG to IgA in SERUM
6:1
LEAST ABUNDANT Ab in SERUM
IgE
MOST EFFECTIVE in COMPLEMENT FIXATION
IgM
LONGEST HINGE REGION
IgD
LONGEST HINGE REGION in IgG CLASSES
IgG3
incomplete or non-agglutinating ab
IgG
significant Ab type often implicated in HTR and HDN
IgG
IgG that CANNOT CROSS THE PLACENTA
IgG2
IgG that is MOST EFFICIENT IN COMPLEMENT FIXATION
IgG3
IgG that CANNOT FIX COMPLEMENT
IgG4
IgGs that have HIGH AFFINITY TO Fc RECEPTORS of phagocytic cells, thus increasing the efficiency of phagocytosis
IgG1, IgG3
an EXCELLENT NEUTRALIZING Ab
IgG
THE ONLY Ab WITH SECRETORY COMPONENTS that protect it from enzymatic digestion while it patrols the sections
IgA
MAJOR Ab FOUND IN THE COLOSTRUM in the mother’s milk
IgA
Ab most often formed IN RESPONSE TO GRAM NEGATIVE BACTERIA
IgM
last to leave in senescence
IgM
first Ab formed by the fetus
IgM
first Ab to appear during an immune response
IgM
Abs in the MEMBRANE OF B CELLS
IgM, IgD
MOST HEAT LABILE Ab
IgE
IgE was originally called
REAGINIC ANTIBODY
2 subclasses of IgA
IgA1, IgA2
subclass of IgA found in the SERUM
IgA1
subclass of IgA found in SECRETIONS
IgA2
IgA2 is held by what chain?
J CHAIN
MOST EFFICIENT Ab that ACTIVATES COMPLEMENT (CLASSICAL)
IgM