SELECTED CYTOKINES AND THEIR FUNCTIONS

Question 1

pro-inflammatory cytokine

Answer 1

IL-1

pro-1nflammatory

Question 2

to Kill cytokine

Answer 2

IL-2

2 (TO) KILL

Question 3

tree of life cytokine

Answer 3

IL-3

tree (3) of life

Question 4

EOSINOPHIL-ACTIVATING CYTOKINE

Answer 4

IL-5

E is the 5th letter of the English alphabet

Question 5

NEUTROPHIL CHEMOTACTIC FACTOR

Answer 5

IL-8

Question 6

aka CACHECTIN; lipopolysaccharide found in gram-neg; secretion of higher levels will lead to septic shock

Answer 6

TNF-a

Question 7

aka LYMPHOTOXIN; for killing and endothelia activation

Answer 7

TNF-β

Question 8

induce production of proteins and pathways that directly interfere with viral replication and cell division

Answer 8

TYPE 1 IFN

Question 9

what IFN is secreted by LEUKOCYTES?

Answer 9

IFN-a

Question 10

what IFN is secreted by FIBROBLASTS?

Answer 10

IFN-β

Question 11

MOST POTENT ACTIVATOR OF MACROPHAGES and boosts their tumoricidal activity

Answer 11

TYPE 2 IFN

Question 12

a factor that induces antiproliferative activity of cells

Answer 12

TGF-β

Question 13

acts as a control to DOWNREGULATED THE INFLAMMATORY RESPONSE WHEN NO LONGER NEEDED

Answer 13

TGF-β