Supplements Flashcards
What is nutritional supplementation?
CHO loading, protein shakes, sports drinks
What is pharmaceutical supplementation?
drugs, pro hormones, hormones
What is nutraceutical supplementation?
components of everyday food taken in unusually large doses
What are the three supplements that are not banned which work?
Creatine
Caffeine
Bicarbonate
What is creatine?
naturally occurring nutrient produced by body at 2g/day
found in meat and fish
taken up by muscle and converted to phosphocreatine
How does creatine work?
If you increase the amount of PCr then you can stop the decline of ATP and increase the rate of resynthesis of ATP
What is the recommended dose? (Test)
initial ingestion of 20g/day can increase muscle Cr by 40% in 6days usually given in 4 5g portions
Further ingestion of 2g/day maintains these elevated Cr levels but does suppress the body creating it
What is the lower recommended dose of creatine?
3g/day will increase muscle Cr but takes 28 days to do so
coingestion of CHO and creatine may increase the storage of Cr
does creatine improve performance?
Yes it significantly decreases time in sprints
and increases speed
can improve strength in trained muscle
increases body mass by 1-2kg
what are the adverse effects of creatine?
GI problems CV problems muscular problems altered kidney function altered liver function
how does caffeine work?
increases lipolysis and sparing of muscle glycogen.
increased adrenaline conc stimulates lipolysis
antagonises adenosine receoptors that limit hormone sensitive lipase and FA oxidization
inhibits phosphodiesterase resulting in increased cAMP
What are some athlete concerns with caffeine?
dehdyration overarousal long lasting side effects (weakness/tachycardia) dependency performing 'drug free'
How does caffeine increase the excitability of muscle fibres?
has a direct influence on regulatory enzymes
increases influx of calcium from ECM
increases release if calcium from the sacrosplasmic reticulum
increases sensitivity of myofilaments to Ca
How does caffeine influence signal transduction from the brain to the motor neuron?
stimulates catecholamine release and the release of NTs
May lower excitation threshold for motor neuron recruitment
alters excitation/contraction coupling
increases transport within the muscle
facilitates transmission of nervous signals
What is the recommended dose of caffeine? (test)
ingesting 2-9mg/kg has bee postulated to elicit ergogenic benefits
higher dose 9-13mg/kg have been associated with GI distress, impaired coordination and diueresis
typically administered 30-60 min prior to exercise