SUPERFICIAL MYCOSES Flashcards

1
Q

What are the predisposing factors of SUPERFICIAL MYCOSES AND DERMATOPHYTOSIS?

A

o Humidity
o Immunosuppression
o Poor hygiene

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2
Q

fungi that require keratin for growth

A

Dermatophytes

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3
Q

Hair infection with nodular masses of fungal
elements surrounding the shaft

A

Piedra

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4
Q

• Infections of the skin
• Macular patches that are non-scaly

A

Tinea

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5
Q

What are the causative agents of superficial mycoses?

A

• Malassezia furfur
• Exophiala werneckii
• Trichosporon beigelli
• Piedraia hortae

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6
Q

These are the causative agents in the skin.n

A

Malassezia furfur and Exophiala werneckii

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7
Q

These are the causative agents in the hair,

A

Trichosporon beigelii and Piedraia hortae

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8
Q

What is the appearance of Malassezia furfur microscopically?

A

Thick, round oval in clusters

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9
Q

Lipophilic yeast
Found as normal flora on the skin

A

Malassezia furfur

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10
Q

(char. By
superficial, brownish, scaly areas in light-
skinned ind. and lighter areas in dark-skinned

A

Pityriasis versicolor/tinea

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11
Q

Give 2 diseases caused by Malassezia furfur

A

Pityriasis versicolor/ Tinea versicolor
Pityriasis folliculitis
• Seborrheic dermatitis; Dandruff
• Systemic infection

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12
Q

What is the most common presentation of the major clinical manifestation of Malassezia furfur?

A

Fawn-colored macules

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13
Q

What are the clinical manifestations of Malassezia furfur?

A

Hyper/hypopigmented
Lesions are well demarcated
Fawn-colored macules

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14
Q

Malassezia furfur is positive to this light green fluorescence.

A

Wood’s lamp

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15
Q

Follicular papules and pustules
Itchy and often appear after sun exposure

A

Pityriasis folliculitis

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16
Q

small circumscribed elevation

A

Papule

17
Q

small inflammatory swelling containing
pus

A

Pustule

18
Q

Changes in quantity and composition of sebum
Increase in alkalinity of skin
• External local factors such as occlusion

A

Seborrheic dermatitis

19
Q

greasy condition of the scalp, face, sternal region
and elsewhere due to overactivity of sebaceous glands (may
result to alopecia, acne

A

Seborrhoea

20
Q

What are the clinical manifestations of seborrheic dermatitis?

A

•Erythema and scaling in areas with a rich supply of
sebaceous glands
• Lesions are covered with greasy scales
• Itching is common in the scalp

21
Q

Common among infants as catheter acquired

A

Systemic Infection

22
Q

What is the laboratory diagnosis of systemic infection of malassezzia furfur?

A

Skin scrapings
Blood
Indwelling catheter tips

23
Q

What is used for the direct microscopy of systemic infection of M. furfur?

A

10% KOH ((glycerol with Parker ink or Calcofluor white)

24
Q

What are the characteristics of the systemic infection of the M. Furfur?

A

o Clusters of thick-walled round budding
yeast-like cells
o Short angular hyphal forms
o Yeast cells (3-7um)

“Spaghetti and Meatballs”

25
Q

What is the measurement of yeast cells under the systemic infection of M.furfur?

A

3-7um

26
Q

What is the initial clue of systemic infection of M.furfur?

A

lack of growth in the
absence of oil

27
Q

A specialized isolation
medium containing glycerol-mono-
oleate. It is a resembling bacteria-like
colonies

A

Dixon’s agar

28
Q

This is a culture medium used for the systemic infection of malessezia furfur.

A

Sabouraud’s dextrose agar or Sheep blood agar
containing Acti-Dione with olive oil

29
Q

What is the microscopic appearance of malassezia furfur?

A

Broad-based buds
The collarettes of the phialides
appear as distinct dark rings
separation the mother &
daughter cells

30
Q

What is the other helpful features in detecting the systemic infection of M.furfur?

A

• White discoloration of skin or light brown discoloration
• Spaghetti and meatballs
• Oil and FA requirement

31
Q

Mould

A

Exophiala werneckii

32
Q

What is the disease associated with Exophiala werneckii?

A

Tinea nigra

33
Q

• Chronic superficial fungal infection of the palms
• Brown to black macules (palmar, plantar, and other
surfaces of the skin)
• Well-defined dark patch with irregular margin, 1-5 cm
in diameter on palm; “stained appearance”
• Lesions: non-inflammatory and non-scaling
• Both tropics and temperature zones
• Usually less than 20 years old female (3:1)
• Predisposing factor: excessive sweating

A

Tinea nigra

34
Q

Under Tinea Nigra, what is the measurement of the dark path with irregular margin on the palm?

A

1 - 5cm

35
Q

What is the predisposing factor of Tinea nigra?

A

Excessive sweating

36
Q

What is the laboratory diagnosis of exophiala werneckii?

A

Skin scrapings

37
Q

What is the primary isolation media of exophiala werneckii?

A

Sabouraud’s dextrose agar

38
Q

Pigmented brown to black (dematiaceous)
septate hyphal elements

A

Sabouraud’s dextrose agar

39
Q

• Initially colonies are mucoid, yeast-like and shiny black
(young yeast)
• Abundant aerial mycelia and become velvety, dark
olivaceous in color (mature mold)
• Serology not required for diagnosis

A

Exophiala werneckii