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Pharm test 3 > sulfas > Flashcards

sulfas Flashcards

1
Q

Sulfas- MOa

A

inhibit folate so can’t synthesize DNA, bacteriostatic

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2
Q

Sulfas - spectrum

A

broad; gram + cocci (including MRSA), gram - bacilli, chlamydia, some fungi, E.coli, UTI’s

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3
Q

sulfas- AE

A

hypersensitivity (Steven’s Johnson, photosensitivity, hemolytic anemia in pts with G6PD deficiency, kernicterus in newborns, renal damage (decreased dose in patients with renal impairment); drink lots of water

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4
Q

sulfas- contrindications

A

infants < 2mo, in 3rd trimester, BF, older adults

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5
Q

sulfas- interactions

A

can intensify warfarin, phenytoin, and sulfa type hypoglycimides (glyburide)

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6
Q

trimethoprim- spectrum

A

gram - bacilli (E.coli, proteus mirabilis, salmonella0 and some gran + diptheria) some protazoa ( taxoplasma gondii) and 1 fungus

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7
Q

TMZ/SMZ -uses

A

UTI’s and 1st choice for p. jirovecii, otitis media, and acute chronic bronchitis 9H.influenzae, or strep PNA

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8
Q

TMZ-SMZ- AE

A

hypersensitivity (Steven’s Johnson, photosensitivity, hemolytic anemia in pts with G6PD deficiency, kernicterus in newborns, renal damage; drink lots of water, birth defects

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9
Q

UTI- Acute cystitis uncomplicated 1st line

A

TMZ/SMZ (BID 3 days), nitrofurantoin (BID5 days), fosfomycin (once)

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10
Q

UTI- Acute cystitis uncomplicated 2nd line

A

cipro (BID 3days), Levofloxacin (BID 3 days)

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11
Q

UTI - UTI and pyelonephritis 1st line

A

TMZ/SMZ (BID 14 days), Cipro (BID 5-7 days), Levofloxacin (daily 5-7 days)

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12
Q

UTI - UTI and pyelonephritis - second line

A

Augmentin (BID 10-14 days), cefadroxil , cefdinir, cefpodoxime

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13
Q

Complicated UTI 1st line

A

TMZ/SMZ, cipro, levofalxacin, augentin, cephalexin

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14
Q

nitrofurantoin MOA

A

bacteriostatic

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15
Q

nitrofurantoin Spectrum and Uses

A

gram + and -UTI

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16
Q

nitrofurantoin AE

A

GI, pulmonary reactions, hematologis effects, neuropathy, hepatotoxicity, birth defects

17
Q

nitrofurantoin - contraindictation

A

only in kids 6 and older, no preg women, caution in elderly with renal impairment

18
Q

nitrofurantoin - most used kind

A

macrobid because it is only BID instead of QId like the rest

Pharm test 3 (7 decks)

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