Antivirals

Question 1

Acyclovir - uses

Answer 1

HSV and varicella and CMV

Question 2

Acyclovir AE

Answer 2

oral - rare; IV - renal failure

Question 3

Valacyclovir - uses

Answer 3

herpes labialis, varicella, herpes zoster, herpes simplex genitalis

Question 4

Valacyclovir - AE

Answer 4

thrombotic thrombocytopenia purpura/hemolytic uremic syndrome (in immunocompromised patients)Fam

Question 5

Pencyclovir/famciclovir

Answer 5

acute herpes zoster and herpes simplex genitalis

Question 6

Ganciclovir Uses

Answer 6

CMV in immunocomprimised patients

Question 7

Ganciclovir- AE

Answer 7

granulocytopenia, thrombocytopenia

Question 8

Ganciclovir- education

Answer 8

male - sterility, women should not become pregnant, advise to report bone marrow suppression symptoms, carcinogenic

Question 9

Valganciclovir Uses

Answer 9

CMV retinitis and prevention of CMV in high risk organ transplant patients

Question 10

Oseltamivir (Tamiflu) uses

Answer 10

flu in children over the age of 1

Question 11

Oseltamivir (Tamiflu) AE

Answer 11

nausea - give with food

Question 12

zanamivir (Relenza)

Answer 12

inhaled - do not give in patients with asthma

Question 13

Chlamydia tx - adults

Answer 13

Azithromycin once or Doxycycline BID x 7 days

Question 14

Gonorrhea (urethritis, cervitis, proctitis pharyngitis)- tx

Answer 14

ceftriaxone IM x1 plus azithromycin POx1

Question 15

trichomoniasis- tx

Answer 15

Metrodonizole or tinidazole

Question 16

nongonococcal urethritis - tx

Answer 16

azithromycin PO x1 or doxycycline BID x 7 days