PCN

Question 1

PCN - MOA

Answer 1

bacteriocidal - disrupts cell wall/B-lactam wall

Question 2

PCN - classifications (narrow/broad)

Answer 2

PCN G - narrow
Amp and Amox - broad
PCNase resistant - narrow

Question 3

what do PCN - G and V (oral) treat

Answer 3

narrow spectrum - treats Strep

Question 4

What does Nafcillin, Oxacillin, Dicloxacillin treat

Answer 4

narrow - Staphylococcus aereus

Question 5

What does Ampicillin and Amox treat

Answer 5

broad - H. influenza, E.coli, Protues mirabilis, and Neisseria gonorrea

Question 6

What type of bacteria does PCN G treat

Answer 6

Gram +, Gram -, anaerobic, and spirochetes, Gram -bacilli are mostly resistant

Question 7

AE of PCN

Answer 7

Allergy is most common; Amp and Amox can cause mild diarrhea

Question 8

hospital acquired MRSA - tx

Answer 8

IV Vanc and linezolid - 1ST CHOICE
daptomycin
telavacin
CLINDA AND CEFTROLINE

Question 9

community acquired MRSA - tx

Answer 9

carrier - mupirocin and retapamulin
can sometimes be tx with just I&D
trimethoprim/sulfamethoxazole, minocycline. doxcycline, or clinda