Sulfa drugs/Cyp450 Flashcards

1
Q

Sulfa drugs

A

sulfonamide abx, sulfasalazine, probenecid, furosemide, acetazolamide, celexcoxib, thiazides, sulfonylureas

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2
Q

sulfa ADR

A

fever, UTI, SJS, hemolytic anemia, thrombocytopenia, agranulocytosis, urticaria (hives)

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3
Q

drugs affected by Cyp

A

anti-epileptics, warfarin, theophylline, OCP

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4
Q

Cyp Inducers

A

“Guinness, Corona, and PBRS induce Chronic Alcoholism”

Griseofulvin
Carbamazepine
Phenytoin
Barbituates
Rifampin
St. John's Wart
Chronic Alcohol use
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5
Q

Cyp inhibitors

A

CRACK AMIGOS

Ciprofloxacin
Ritonavir (protease inhibitors)
Amiodarone
Cimetidine
Ketoconazole
Acute Alcohol Use
Macrolides
Isoniazid
Grapefruit Juice
Omeprazole
Sulfonamides
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