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ADRs Flashcards

1
Q

coronary vasospasm

A

cocaine, sumatriptan, ergot alkaloids, amphetamines

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2
Q

cutaneous flushing

A

Vanc, adenosine, niacin, Ca2+ channel blockers, echinocandins (“VANCE”)

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3
Q

dilated cardiomyopathy

A

anthracyclines (doxorubicin, daunorubicin)

prophylaxis: dexrazoxane

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4
Q

torsades de pointes (dIT)

A

Postassium Channel Blockers (III), Sodium channel blockers (IA), macrolides, haloperidol, choroquine, protease inhibitors

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5
Q

tordsades de pointes (FA)

A

antiArrythmics, antiBiotics, antipsychotics, antiDepressants (TCA), antiEmetics(ondansetron) (ABCDE)

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6
Q

adrenocortical insufficiency

A

HPA suppression 2* to glucocorticoid w/d

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7
Q

hot flashes

A

tamoxifen, clomiphene

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8
Q

hyperglycemia

A

tacrolimus, protease inhibitors, niacin, HCTZ, corticosteroids

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9
Q

hypothyroidism

A

lithium, amiodarone, sulfonamides

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10
Q

acute cholestatic hepatitis, jaundice

A

emycin

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11
Q

focal to massive hepatic necrosis

A

Halothane, amanita phalloide, valproic acid, acetaminophen

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12
Q

hepatitis

A

Isoniazid, pyrazinamide, statins, fibrates

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13
Q

pancreatitis

A

Didanosine, corticosteroids, alcohol, valproic acid, azathioprine, diuretics

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14
Q

pill-induced esophagitis

A

tetracyclines, bisphosphonates, KCl

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15
Q

pseudomembranous colitis

A

clindamycin, ampicillin, cephalosporins

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16
Q

cholinesterase inhibitor toxicity sx

A

diarrhea, urination, myosis, bradychardia, bronchospasm, excitation of sk m/CNS, lacrimation, sweating, salivation

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17
Q

hypertensive crisis

A

MAOI + tyramine (alcohol, cheese)

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18
Q

agranulocytosis

A

clozapine, carbamazepine, propylthioruracil, methimazole, colchicine, ganciclovir

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19
Q

aplastic anemia

A

carbamazepine, methimazole, NSAIDS, benzene, chloramphenicol, propylthiouracil

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20
Q

direct coombs positive hemolytic anemia

A

methyldopa, PCN

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21
Q

gray baby syndrome

A

chloramphenicol

22
Q

hemolysis in G6PD deficiency

A

Isoniazid, sulfonamides, dapsone, primaquine, aspirin, ibuprofen, nitrofurantoin, fava beans

23
Q

megoBLAStic anemia

A

phenytoin, methotrexate, sulfa drugs

“have a Blast w/ PMS”

24
Q

thrombocytopenia

A

heparin, cimetidine

25
Q

thrombotic complications

26
Q

Fat redistribution

A

protease inhibitors, glucocorticoids

Fat PiG

27
Q

gingival hyperplasia

A

phenytoin, ca2 channel blockers, cyclosporine

28
Q

hyperuricemia

A

pyrazinamide, thiazides, furosemide, niacin, cyclosporine

29
Q

myopathy

A

statins, niacin, colchicine

30
Q

osteoporosis

A

corticosteroids, heparin

31
Q

photosensitivity

A

Sulfonamides, Amiodarone, Tetracyclines, 5-FU

“SAT For Photo”

32
Q

Steven-Johnsons Sx

A

anti-epileptic drugs, allopurinol, sulfa drugs, PCN

33
Q

SLE-like sx

A

sulfa drugs, hydralazine, isoniazid, procainamide, phenytoin

“SHIPP”

34
Q

teeth discoloration

A

tetracylcines

35
Q

tendon issues

A

fluorquinolones

36
Q

cinchonism

A

quinidine, quinine

37
Q

parkinsonlike sx

A

antipsychotics, reserpine, metoclopramide

38
Q

seizures

A

isoniazid (vit b6 deficiency), bupropion, imipenem/cilastatin, tramadol, enflurane

39
Q

tardive dyskinesia

A

antipsychotics, metoclopramide

40
Q

diabetes insipidus

A

lithium, demeclocycline

41
Q

fanconi syndrome

A

tenofovir, ifosafamide

expired tetracycline

42
Q

heme cystitis

A

cyclophosphamide, ifosfamide,

43
Q

interstitial nephritis

A

methicillin, NSAIDS, furosemide

44
Q

SIADH

A

carbamazepine, cyclophosphamide, SSRI

45
Q

dry cough

46
Q

pulmonary fibrosis

A

methotrexate, nitrofurantoin, carmustine, bleomycin, busulfan, amiodarone

47
Q

antimuscarinic

A

atropine, TCA, H1-blockers, antipsych

48
Q

disulfiram-like rxn

A

metronidazole, cephalosporin, griseofulvin, procarbazine, 1stgen sulfonylureas

49
Q

nephrotoxicity/ototoxicity

A

aminoglycosides, vancomycin, loop diuretics, cisplatin

50
Q

nephrotoxicity/neurotoxicity

A

aminoglycosides, cisplatin, polymixins

51
Q

gynecomastia

A

“STACKED”

Spirinolactone, Digoxin, Estrogens, Cimetidine, Alcohol (chronic), Ketoconazole, THC

step 1 pharm (8 decks)

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