Sugammadex

Question 1

Sugammadex Class

Answer 1

Reversal Agent for Steroidal Non-Depolarizing NMB

Question 2

Sugammadex MOA

Answer 2

Irreversibly encapsulates, deactivating, steroidal non-depolarizing neuromuscular blocking agents

Question 3

Sugammadex Dosing

Answer 3

Reversal of profound block
Post tetanic count < 2: 16 mg/kg
Post tetanic count > 2: 4 mg/kg
TOF 1-4 count: 2-4 mg/kg

Question 4

Sugammadex Onset

Answer 4

1 minute

Question 5

Sugammadex Metabolism

Answer 5

Not Metabolized

Question 6

Sugammadex Excretion

Answer 6

Kidneys

Question 7

Sugammadex Admin Considerations

Answer 7

Hypersensitivity Reaction (Anaphylaxis)

Blocks oral contraceptive effects for up to 7 days (risk for pregnancy)

Must use succinylcholine or a bezylisoquinoline non-depolarizing agent is paralysis is needed after administration