SUD 3 Flashcards

1
Q

What is the most common neurological manifestation of chronic ETOH use disorder?

A

Neuropathy (nearly 75%)

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2
Q

PCP’s effects are mediated by it’s action on what receptor?

A

PCP = potent NMDA receptor antagonist.

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3
Q

Heroin/opioid withdrawal presents with what symptoms?

A
  1. dysphoric mood
  2. N/V
  3. Muscle ache and twitching
  4. Lacrimation and rhinorrhea
  5. Diaphoresis
  6. Diarrhea
  7. Dilated pupils
  8. piloerection
  9. yawning
  10. Hyper or hypo thermia
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4
Q

Heroin can be detected in urine drug screen up to how long after use?

A

72 HOURS (3 days)

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5
Q

What is the most widely abused drug among HS students in USA?

A

Marijuana

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6
Q

Chronic abuse of hydrocarbon inhalants (glue,paint thinner) can cause what neurological problem?

What end organ problems can you see with chronic heavy abuse?

A

Distal sensorimotor polyneuropathy - Starts with distal numbness and tingling and later motor weakness.

End organ - renal failure, liver failure, bone marrow suppression.

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7
Q

What drug is the most significant contributor to drug induced stroke, accounting for nearly 50% of all cases?

A

COCAINE.

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8
Q

TRUE or FALSE,

Some studie shave found Carbamazepine as effective in Etoh withdrawal as BZDs.

A

TRUE

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9
Q

PCP exerts it’s hallucinogenic effect by what mechanism?

A

NMDA receptor antagonism

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10
Q

Which lab value abnormality MOST RELIABLY detects alcohol abuse?

A

GGT (it is elevated in 80% of those with alcohol use)

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11
Q

Which illegal drug accounts for the most drug related ED visits?

A

Cocaine.

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