Studying the Brain Flashcards

1
Q

What is a post-mortem examination?

A

This is a technique involving the analysis of a person’s brain following their death.

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2
Q

In psychological research, whose brains are likely to be examined? What is examined? Why?

A

Those who have a rare disorder and have experienced unusual deficits in mental processes or behaviour during their lifetime.

Areas of damage within the brain are examined after death as a means of establishing the likely cause of the affliction the person experienced.

This may also involve comparison with a neurotypical brain in order to ascertain the extent of the difference.

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3
Q

What are 3 strengths of a post-mortem?

A

Post-mortem evidence was vital in providing a foundation for early understanding of key processes in the brain.

Paul Broca and Karl Wernicke both relied on post-mortem studies in establishing links between language, brain and behaviour decades before neuroimaging ever became a possibility.

Post-mortem studies were also used to study HM’s brain to identify the areas of damage, which could then be associated with his memory deficits.

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4
Q

What are 3 limitations of post-mortems?

A

Causation is an issue. Observed damage to the brain may not be linked to the deficits under review but to some other unrelated trauma or decay.

Post-mortem studies raise ethical issues of consent from the individual before death.

Participants may not be able to provide informed consent, for example in the case of HM who lost his ability to form memories and was not able to provide such consent - nevertheless post-mortem research has been conducted on his brain. This challenges the usefulness of post-mortem studies in psychological research.

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5
Q

What does fMRI stand for?

A

Functional magnetic resonance imaging. ​

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6
Q

What are 2 strengths of fMRI?

A

fMRI does not rely on the use of radiation. If administered correctly it is virtually risk-free, non-invasive and straightforward to use.

Produces images that have very high spatial resolution, depicting detail by the millimetre, and providing a clear picture of how brain activity is localised. This means that fMRI can safely provide a clear picture of brain activity.

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7
Q

What are 2 limitations of fMRI?

A

fMRI is expensive compared to other neuroimaging techniques.

It has poor temporal resolution because there is around a 5-second time-lag behind the image on screen and the initial firing of neuronal activity. This means fMRI may not truly represent moment-to-moment brain activity.

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8
Q

How does fMRI work?

A

Works by measuring the energy released by haemoglobin (Hb - the protein content of blood – this is the part of the red blood cell that binds with O₂). ​

When Hb is bound to O₂ it reacts differently to when it is without O₂. ​

When an area is more active, blood flow is directed to that area (haemodynamic response).

The difference in the amount of energy released by the Hb is detected by the moving scanner and the change measured. ​

This gives us a dynamic (moving) image of the brain and shows us a 3D image which allows us to map which parts of the brain are involved in particular mental processes – this has important implications for our understand of localisation of function. ​

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9
Q

What is the temporal duration of fMRI? At what distance does is it accurate?

A

fMRI shows activity about 5 seconds after it occurs.

It is also accurate within 1-2mm in the brain. ​

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10
Q

Outline fMRI use with lie detectors

A

Analysis of neural blood flow is preferable to tracking peripheral measures of anxiety that would be measured by more traditional lie detectors or polygraphs.

Traditional lie detectors are widely acknowledged as being “beatable” but neural activity is much more difficult to fake.​

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11
Q

What is a strengths of using fMRI as a method of lie detection?

A

Specificity in lie detection may be higher than that of the polygraph.

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12
Q

What are 2 limitations of using fMRI as a method of lie detection?

A

Most scientists currently agree that fMRI research evidence is still weak and lacks both external and construct validity (Spence, 2008).

The current state of the science does not, at this time, meet the legal standards in court proceedings.

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13
Q

What does EEG stand for?

A

Electroencephalogram

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14
Q

What are 2 limitations of an EEG?

A

Main drawback lies in the generalised nature of the information received.

The EEG signal is not useful for pinpointing the exact source of neural activity. Therefore it does not allow researchers to distinguish between activities originating in different but adjacent locations. (Low spatial resolution).

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15
Q

What are 3 strengths of an EEG?

A

Useful in studying the stages of sleep and in the diagnosis of conditions such as epilepsy - can easily be detected on screen.

EEG technology has extremely high temporal resolution.

Today’s EEG technology can accurately detect brain activity at a resolution of a single millisecond or less. This shows the real-world usefulness of the technique.

This technique is much cheaper than others (such as fMRI) so are more widely available.

They require a level of expertise in order to interpret the data gathered.

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16
Q

What does an EEG do?

A

Measures electrical activity within the brain via electrodes that are fixed to an individual’s scalp using a skull cap.

17
Q

What does an EEG scan recording represent?

A

The brainwave patterns that are generated from the action of thousands of neurons, providing an overall account of brain activity.

18
Q

When is an EEG often used?

A

EEG is often used by clinicians as a diagnostic tool as unusual arrhythmic patterns of activity (i.e. no particular rhythm) may indicate neurological abnormalities such as epilepsy, tumours or disorders of sleep.

19
Q

What does ERP stand for?

A

Event-related potentials.

20
Q

What are 2 limitations of an ERP?

A

There is a lack of standardisation in ERP methodology between different research studies which makes it difficult to confirm findings.

In order to establish pure data in ERP studies, background ‘noise’ and extraneous material must be completely eliminated. This is a problem because it may not always be easy to achieve.

21
Q

What are 2 strengths of an ERP?

A

They bring much more specificity to the measurement of the neural processes than could ever be achieved using raw EEG data. ​

Researchers have used different types of ERP reading to describe the precise roles of cognitive functions, e.g. P300 involved in the WM’s maintenance.

A useful method to test the reliability of self-report answers. They are a useful supplementary method for research, particularly when the area of research is potentially sensitive and open to social desirability bias.

22
Q

ERPs use the same equipment as what other brain studying technique?

A

ERPs use the same equipment as EEGs.

23
Q

What are EEGs?

A

EEGs have many specific and clinical applications but in its raw form it is a crude and overly general measure of brain activity. ​

24
Q

What is contained in EEG data?

A

Within EEG data are contained all the neural responses associated with specific sensory, cognitive, and motor events that may be of interest to cognitive neuroscientists. ​

25
Q

What can researchers do with the responses displayed by EEG data?

A

Researchers can tease out and isolate these responses. ​​

26
Q

What do statistical averaging techniques do?

A

Using statistical averaging technique, all extraneous brain activity from the original EEG recording is filtered out leaving only those responses that related to the presentation of a specific stimulus or performance of a specific task.​

What remains are ERPs: types of brainwave that are triggered by particular events, stimuli introduced by the researcher.​

Research has revealed many different forms of ERP and how, for example, these are linked to cognitive processes such as attention and perception.

27
Q

What did Costa et al do in 2003?

A

Used ERPs to record responses to nude pictures of both sexes in young people (aged 19-29 years).

When asked about how they felt, men general said they were aroused by the nude female pictures, whereas women mostly reported to have neutral feelings to both male and female nude pictures.

However, when Costa et al examined the ERP’s of both males and females they found a higher response to opposite-sex nude pictures than reported by the participants.

This seems to suggest that this method of measuring activity has greater accuracy than self-report.