Study Set Test 1 Pharmacy Flashcards
Isotopes have the same # of ?
Protons
Isotopes will have different number of ?
Neutrons
Isotopes will belong to the same ?
Element
Isotopes mass number will be ?
Different
Isobars have the same number of ?
Nucleons
Isobars have the same______ &______ ?
Mass number & Atomic number
Isobars will belong to a different?
Element
Isotopes the mass number increases by what ?
1
Isobars the protons increase or decrease?
Increase
Isobars the neutrons _______?
Decrease
Isotones have the same number of ?
Neutrons
Isotones will belong to a different?
Element
Isotones will have different number of _______ and ______?
Protons and Nucleons
Isotones the ____ will increase ?
Protons
Isomers have the same number of ?
Protons and neutrons
Isomers have the same element ? T/F
True
Isomers only differ by ?
Energy
Four Classification of nuclides?
Isotopes
Isobars
Isotones
Isomers
What are the different types of radiation?
Alpha/Beta/Positron/Electron Capture/Isomeric/Fission
Alpha is the slowest and least penetrating due to its :
Size
Alpha radiation is
A particle it has mass
Alpha is emitted from the :
Nucleus of an atom
As the size of radiation increases, penetration and speed ?(Alpha)
Decrease
An Alpha particle will only travel_____ in the air can be stopped by ______?
3cm, a piece of paper
Alpha particle contains an average of _______ of energy?
4 MeV
Beta is actually a high speed electron coming from the …
Nucleus
Beta is ______ the size and weight of Alpha?
Half
Beta is a little faster and more penetrating than _____ particle?
Alpha
______ can be stopped several meters in the air and can be stopped by a few cm of tissue or small piece of wood.
Beta
____ is not as big as ____?
Beta, Alpha
Positron B+ is a high speed ______ coming from the nucleus
Electron
_______ has the same properties of Beta
Positron B+
Gamma Ray is not a ?
Particle
______ has no physical size or discernible mass to it.
Gamma ray
Gamma rays originate from ?
Nucleus
Fastest form of radiation? Can travel the speed of light
Gamma Ray
Highly penetrating can go through skin and body tissue and take several feet of concrete to stop
Gamma ray
Virtually identical to gamma ray
X rays
Originate from the orbital shells outside the nucleus
X rays
T1/2 equals
Physical half life
The time required for a radionuclide to decay to half of its activity.
Physical half life
Ex: If a sample of 99mTc had 100 mCi at 6 am it would have _____ at noon?
50 mCi
MCI =
Millicuries
The time it takes for ____% of a radiopharmaceutical to leave the body via normal physiologic functions is ?
50/Biologic half life
Physiologic Functions include:
Feces/Urine/Vomit/Sweat/Breathing
Tb1/2 equals
Biologic half life
This will vary for every radiopharmaceutical and individual person…. What am I?
Biologic half life
The time it take for ____% of radiopharmaceutical to leave the body via normal physiologic and decay of the radionuclide.
Effective half life
Te1/2 equals
Effective half life
This is always less than tb1/2 and t1/2
Te1/2
Formula of half life equals
1/te1/2 =1/Tp1/2 + 1/tb1/2
A nuclide that is unstable is
Radionuclide
To achieve stability and nuclide must undergo… a stable ratio is N/Z
Decay
Six ways a radionuclide can decay ?
Alpha/Beta/Positron/EC/Isomerism/Fission
Beta Decay is _____ rich
Neutron( add proton)
Positron Decay is _______ rich?
Proton( subtract - proton)
Electron capture is _____ rich
Proton ( subtract proton)
Alpha Decay usually occurs in heavy ______
Nuclei atomic number is usually 85 and higher ex:radon
When a radionuclide decays by _____ it emits a heavy charged particle which is ____ and ____?
Alpha /2 protons and 2 neutrons
Alpha is a ____?
Helium
What energy is given off in the form of antineutrino or v~
Beta
A neutron is converted to a proton ?
Beta
Antinineurto is a particle with ?
No charge it carries away excess energy
The particle emitted is e+ what am I ?
Positron
Neutrino is used in ?
Positron and EC
Character x rays are emitted from the shells outside the nucleus in this decay
Electron Decay
The nucleus captures an electron and combines with a proton to make a neutron
Electron Capture
When Electron capture happens it takes from the closest shell T/F
True
Parameters for electron capture to occur
The energy difference between parent and daughter radionuclide are less than 1.02 MeV
Energy difference greater than 1.02 MeV usually by
Poistron
The probability of EC occurring increases with ?
2 protons
Isomeric transition
Occurs when the nucleus of a radionuclide is in an excited state
Also referred to gamma decay is ?
Isomerism transition
When the isomeric state decays to a lower excited state is
Isomeric Transition
Remaining in an excited state
Metastable state
When a radionuclide decays by IT is gives off a
Gamma ray
Isomerism can occur by itself or by
Beta/positron/ec
Internal Conversion
Makes a conversion electron or an auger electron
Occurs in radionuclides with a heavy nucleus
Fission
Fission fragments
2 fragments
Fission makes how many neutrons
2 to 3 neutrons
Energy of fission is
200-400 MeV
Probability of Fission is …
Low
Decay schemes will display
Modes and frequency of decay/process of decay/energy of different radiation emitted/half life
All positrons and EC decay by which arrow
Decay arrow to the left
Beta decay scheme
Decays with arrow pointing to the right
All Gamma decay scheme is
Arrow down 180 degree
A nucleus in an excited state has_________ lines above ground
Horizontal
The radioactivity per unit mass of a radionuclide or radiopharmaceutical.
Specific Activity
Is commonly used in production of radionuclides
Specific activity
mCi/mg , MBq/mg , Ci/g
Specific Activity is defined by activity/weight
Always express specific activity in _____ form
Lowest
The radioactivity per unit volume of a radionuclide or radiopharmaceutical.
Activity concentration
Is commonly used when referring to radiopharmaceutical doses or activity taken from a generator.
Activity Concentration
Defined as activity/volume
Activity concentration
mCi/ml is the most common form
Activity concentration
Injected into patients for diagnostic and theraputic purposes
Radioactive drugs
Originally called :
Radio tracers they are radioactive drugs that traces a pattern throughout the body
Emits the radiation from the radiopharmaceutical?
Radionuclide
Exhibits a response on the body to direct the radiopharmaceutical to its origin of the body
Pharmactical
The size of an atom
10-8 cm or 1 angstrom
The size of the nucleus is
10-13 or 1 fermi
Nuclei containing 2/8/20/50/82
Magic numbers
Electron Mass
9.1x10-31 kg
Protons Mass
1.67x-27kg
Neutron Mass
1.67x-27 kg
Protons energy
+1.6x10-19 coulombs
Electrons energy
-1.6x10-19 coulombs