study questions wk 6 Flashcards
immature RBCs in order from least mature to most
1.rubriblast
2.prorubrictye
3.basophilic reticulocyte
4.polychromatophilic reticulocyte
5.metarubricyte
6.reticulocyte
characteristics of rubriblast
-small round nucleus
-one or more nuclei
-small amount of basophilic cytoplasm
characteristics of prorubricyte
-smaller than rubriblast
-slightly more dense basophilic cytoplasm
-no visible cytoplasm
characteristics of basophilic rubricyte
-smaller than prorubricyte
-clumping nucleus
-basophilic
characteristics of polychromatophilic rubricyte
more condensed and clumped nucleus than basophilic; pink cytoplasm
characteristics of metarubricyte
-smallest cell
-condensed nucleus
-deep red cytoplasm
-cannot divide
characteristics of reticulocytes
-immature RBC
-organelles
-polychromatophils
-small pieces remain (seen on blue stain)
-no nucleus seen
it is normal for dogs and cats to have a small percentage of reticulocytes in their blood
true
when are more immature forms of RBCs found in blood
older cell type; if hemorrhage or premature RBC destruction occurs
if you see rubricytes on a blood smear it is likely there are multiple of what other 2 immature RBC types
metarubricytes and polychromatophils
3 immature stage of thrombocytes from least mature to most
megakaryoblast
promegakaryocyte
megakaryocyte
cells in the granulocyte series are divided into the proliferation pool and maturation pool. proliferation pool represents cells which are capable of mitosis:
myeloblasts
promyelocytes
myelocytes
cells of maturation pool
band cells and (segmented granulocytes) metamyelocytes
characteristics of myeloblasts
-large with round to oval nucleus
-prominent nucleolus
-pale blue-grey cytoplasm
-immature RBCs
-contain organelles
characteristics of promyelocytes
-large
-pale staining
-prominent reddish granules
-no obvious nuclei
characteristics of myelocytes
-smaller with round nucleus
-mature cell characteristics appear
characteristics of metamyelocyte
similar to myelocyte but has indented nucleus
characteristics of band cells
-horse shoe shaped; parallel sides; s-shaped or headphone shaped
-no segmentation
-thicker and larger nucleus
characteristics of monoblasts
similar to myeloblasts but has irregular shaped nucleus
characteristics of promonocytes
similar to myelocytes and metamyelocytes
characteristics of lymphoblasts
-well-defined nuclear membrane
-one or two nucleoli
-the cytoplasm is small or moderate in amount
-gotten larger after being stimulated by an antigen
characteristics of prolymphocytes
-clumped chromatin
-large prominent vesicular nucleolus
-abundant cytoplasm
where do juvenile b lymphs mature
in bone marrow; specialized ileal Peyer patches, or bursa of Fabricius
where do t lymphs mature
in thymus
where do NK cells mature
bone marrow, thymus, or other lymphoid tissue
how to report band cells in CBC report
included as part of 100 WBC count
how to report metamyelocytes in CBC report
reported under abnormal morphology as total number seen
how to report hyper segmented neutrophils in cbc report
reported as percent of neutrophils counted just like toxic segs would be
which immature stage is the first stage where neutrophils, eosinophils, and basophils are distinguished as the identifying granules appear
myelocyte stage
the general trend is for the ___ of the cell to become ___, the nuclear shape to go from ___ to increasingly ___, the nuclear width to become ____, and the cytoplasm to become less ___ as the cell matures
size; smaller; rounded; indented/segmented; narrowed; basophilic
