Structure of Respiratory System Flashcards

1
Q

What is the function of the Respiratory system?

A

Gas exchange, Acid/Base balance, Phonation, Defense mechanisms, Metabolism, Handling bioactive materials

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2
Q

what is the upper airway?

A

Nose, sinuses, larynx

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3
Q

What is the function of the upper airways?

A

“condition” inspired air. (humidify/filter) It also provides a lot of resistance, which can increase when you have an infection.

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4
Q

What is the conducting zone?

The Respiratory zone?

A

Conducting zone-Mouth to terminal bronchioles.

Respiratory zone-respiratory bronchioles to alveoli.

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5
Q

what comprises the bronchus wall?

A

Cilia, pseudostratified columnar epithelium, smooth muscle, MUCUS GLANDS, CARTILAGE

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6
Q

What comprises the brionchiole wall?

A

Cilia, Simple columnar epithelium, smooth muscle, connective tissue

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7
Q

What comprises the alveolus wall?

A

Simple squamous epithelium, connective tissue.

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8
Q

What increases secretions from goblet cells?

A

Smoke Pollutants

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9
Q

What makes up submucosal treacheobronchial glands?

What controls them?

A

Serous and mucus cells

Controlled by SANS and PANS, peptides, inflammatory mediators

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10
Q

What do ciliated epithelial cells produce/absorb?

A

Cl- is produced and secreted

Na+ absorbed

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11
Q

Cystic fibrosis patients cant do what?since

A

abnormal Cl- production

Cant absorb Na+ - thick mucus

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12
Q

Type I cell/Type II cell/alveolar macrophage

A

Covers 90% area/Produce surfactant/phagocytize inspired stuff

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13
Q

What makes up the respiratory unit?

A

Bronchiole, alveolar ducts, atria, alveoli

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14
Q

What is a pore of kohn?

A

pore between alveoli, allows for collateral ventilation

fluid and bacterial can also pass through-bad

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15
Q

What makes up the respiratory membrane?

A

Surfactant fluid around alveoli, alveolar epithelium, epithelial basement membrane, interstitial space, capillary basement membrane, capillary endothelium

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16
Q

What is the lung interstitium composed of?

A

Connective tissue, smooth muscle, lymphatics, capillaries, cells (fibroblasts)

17
Q

What do the fibroblasts in the lung interstitium produce?

A

Collagen and elastin - elastic distention and recoil

18
Q

Describe the parietal pleura.

A

It is a double layer. space between has a tiny amount of fluid. This is important to maintain the neg pressure to produce lung expansion.

19
Q

Does the parietal pleura contain lymphatics?

A

Yes, The openings into the pleural cavity are called stoma, helps to get rid of excess fluid to maintain the cavity

20
Q

What are the components of the parietal pleura?

A

Stomata (lymph vessels), Microvessels are closer to the surface - responsible for the pleural liquid formation in humans

21
Q

What is different about the visceral pleura?

A

No stomata, microvessels are further from the surface

22
Q

What is the purpose of the pleural fluid?

A

Smooth expansion of lungs, transmission of pressure

23
Q

Describe Pleural Effusion

A

Most common in congestive heart failure (increased pulmonary hydrostatic pressure from visceral side),
Increased microvascular hydrostatic pressure
increase microvascular permeability
Decreased clearance rate - systemic venous hypertension
Decreased microvascular oncotic pressure,
decreased pleural pressure
bLockade of lymphatic drainage-disturbed pleural pressure

24
Q

Where do you get airway resistance in the lower respiratory tract?

A

Bronchi and bronchioles (muscle contraction and secretion from glands)

25
Q

describe Type I cells

A

Fewer in number than Type II, flat, cytoplasmic extensions, 95% lining

26
Q

describe Type II cells

A

Thicker, inclusion bodies, surfactant secreting (composed of proteins and phospholipids)