Overview of Obstructive Pulmonary Disorders Flashcards

1
Q

What are the three classification of Obstructive Pulmonary disorders?

A

Obstruction from conditions in the wall of the lumen, related to loss of lung parenchyma, obstruction of airway lumen

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2
Q

What are the disorders from obstruction due to change in condition of the wall of the lumen?L

A

Asthma, acute bronchitis, Chronic bronchitis

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3
Q

What are the disorders from loss of lung parenchyma?

A

Emphysema

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4
Q

What are the conditions from obstruction of the airway?

A

Bronchiectasis, Bronchiolitis, Cystic Fibrosis, Acute tracheiobronchial obstruction, Epiglottitis, Croup

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5
Q

What is the decreasing order of Reversibility with Asthma, Chronic Bronchitis, and Emphysema?

A

Asthma, Chronic Bronchitis, Emphysema

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6
Q

What is the decreasing order of Sputum Production with asthma, chronic bronchitis, and emphysema?

A

Chronic bronchitis, asthma=emphysema

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7
Q

What is the decreasing order of alveolar damage with asthma, chronic bronchitis, and emphysema?

A

Emphysema, Chronic bronchitis, asthma

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8
Q

What is the condition with Increased airway responsiveness to stimuli that is partially or completely reversible?

A

asthma

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9
Q

Which type of asthma has a strong familial connection, shows a positive skin test to allergens, and allergen-specific immunotherapy is helpful, allergenic or non-allergenic?

A

Allergenic

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10
Q

What type of asthma is developed in middle age, is intrinsic, no family history, antigen-antibody reactions are less important, and allergen specific immunotherapy is NOT helpful, allergenic or non-allergenic?

A

Non allergenic

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11
Q

Which type of asthma has a less favorable prognosis, allergenic or non-allergenic?

A

non-allergenic

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12
Q

What is the pathophysiology of allergic asthma?

A

allergen stimulates, inflammatory mediators secrete cytokines that result in hypersecretion of mucus, epithelial shedding, sub epithelial fibrosis, plasma leakage, vasolilation, bronchoconstriction due to parasympathetic activation

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13
Q

Pathological Mechanisms of asthma?

A

Smooth muscle contraction/hyperplasia/hypertrophy, submucosal thickening, mucus, cellular debris in lumen

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14
Q

What are some things you could hear in a history of an asthma patient?

A

Dyspnea, occupational exposure to something

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15
Q

What would you find during a physical examination of an asthma patient?

A

Rapid breathing, tachycardia, pulsus paradoxus (decreased SV during inspiration), accessory muscles used, longer expiratory phase than inspiratory, hyperinflated chest, hyperresonance, WHEEZING

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16
Q

What airflow rates can can confirm asthma?

A

Peak experiatory flow rate (PEFR)
Forced expiratory Volume in first second (FEV1)
Forced mid-expiratory Expiratory Flow Rate (FEF)
all decreased

17
Q

What is the difference with asthma in the Flow-volume curve?

A

There is a shift to the left in observed total lung capacity and residual volume with a greatly decreased expiratory flow. Bigger volume, smaller flow. This gradually returns to normal

18
Q

What are the therapeutic goals for asthma patients?

A

Allow patient to live without too much asthma interference
allow pnt to sleep without awakening
Limit use of rescue bronchodilators
Prevent needs for unscheduled medical care

19
Q

what are the two components of asthma therapy?

A
Acute relievers (rescue treatments)-bronchodilate
Controller treatments-decrease frequency
20
Q

What are rescue treatments for asthma?

A

Beta adrenergic agents - stimulate Beta 2 adrenergic receptors - bronchodilation
Anticholinergics - inhibit effects of acetylcholine on M3 receptors

21
Q

What are controller treatments for asthma?

A

Inhaled Corticosteroids, antileukotrienes, Long-acting beta agonists, theophlline, systemic corticosteroids, anti-ige treatment