Stroke and Vascular Disorders Flashcards

1
Q

What kind of recovery occurs in the first few days after a stroke?

A

natural recovery
Resolution of oedema
Reperfusion of ischemic penumbra

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2
Q

What kind of recovery occurs weeks/months after a stroke?

A

Neuronal plasticity
cortical remodelling
Dendrite sprouting
synaptic remodelling

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3
Q

What disabilities/conditions can occur after a stroke?

A
Post stroke pain
Incontinence
Depression
Visual loss 
Neglect
Agnosias
Dyspraxia
Gait
Spasticity
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4
Q

What is neglect?

A

Can be visual or somatosensory
Feature of RIGHT parietal lobe stroke only
Problem of attention - failure to attend to/ monitor left side
(Think of picture of the one sided clock)

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5
Q

What is agnosias?

A

“Modality-specific inability to access semantic knowledge of an object”
Can apply to any sensory modality
E.g. visual agnosia = unable to recognise object by just looking at it, needs to use other senses too e.g. touch

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6
Q

What is dyspraxia?

A

loss of ability to conceptualise, plan, and execute complex sequence of motor actions - Loss of cortical pathways
Difficulty in: Identifying and knowing how to use objects, copying drawings etc
Lesion can be in left inferior parietal lobe or supplementary motor area

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7
Q

What are meant by ‘transfers’?

A

Devices to move patients from one place to another safely e.g. hoist, banana board
Method chosen depends on: Balance, alertness and cognition

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8
Q

What is taken into consideration when producing a discharge plan for a patient after a stroke?

A

The patient’s abilities: what assistance do they need?
Are any family or friends willing to provide care?
Any foreseeable and modifiable risks?
The environment they will be discharged to? - check accessibility, need for adaptations, hazards

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9
Q

What is a spastic hemiparetic gait?

A

Stiff legged due to spasticity of ankle plantar flexors and knee flexors
Short, slow steps
Risk of falls
Ankle weak, unable to dorsiflex - difficulty on uneven surfaces
Loss of “righting reflexes”

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10
Q

What is the management for gait?

A

Splints to correct foot drop
physiotherapy
manage spasticity
walking aides

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11
Q

What is spasticity?

A

Hyperexcitability of the stretch reflex
May be co-existent tendon or soft tissue shortening
Can lead to:
Loss of function - impaired balance, manual dexterity
Unable to maintain skin hygiene in flexures
Pain

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12
Q

What is the management of spasticity?

A

Physiotherapy and splinting to maintain joint range of movement
Drugs: botulinum toxin injections (local), baclofen (systemic)

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13
Q

What is the impact on family members who have had stroke?

A

Depression and anxiety common in family
Specifically ask about carer strain
Provide information about diagnosis and plan
Ask about arrangements for respite care?
Refer for benefits advice: many carers do not claim benefits they are entitled to
Voluntary organisations e.g. Stroke Association

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14
Q

On what side does weakness occur in comparison to the side of the stroke? And what can weakness of muscles cause?

A

Contralateral
Weakness and incoordination of oropharyngeal muscles
Dysarthria: slurred, indistinct speech
Incoordination of swallowing

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15
Q

Where is Broca’s and what can damage to Broca’s cause?

A

In right handed patient: infero-lateral frontal lobe
EXPRESSIVE DYSPHASIA
Flow of speech: stilted, difficult
Difficulty finding words, e.g. “spoot” for “spoon”
Reading, writing and comprehension relatively intact

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16
Q

Where is Wernicke’s and what can damage to Wernicke’s cause?

A

In right handed individuals: left posterior superior temporal lobe
Flow of speech is fluent, but:
Neologisms (“made up” words)
Mistake closely related words: up/ down, yes/ no,
Comprehension, reading and writing impaired

17
Q

What physiological variables should be controlled after a stroke?

A

Blood pressure - Anti-hypertensive treatment is not recommended after acute stroke, apart from in certain circumstances
Oxygenation
Capillary blood glucose

18
Q

What is used to set goals for rehabilitation?

A
Specific
Measurable
Achievable
Relevant
Time-limited
19
Q

What is post stroke pain?

A

Damage to sensory cortex leads to contralateral sensory disturbance
Can be a negative phenomena - decreased sensation OR
positive phenomena - Paraesthesia, burning, shooting pains
May respond to:
Pregabalin or Gabapentin (anti-epileptic agents)
Amitriptyline (antidepressant) but not paracetamol, opiates or NSAIDs

20
Q

What is the definition of a TIA?

A

Neurological Deficit lasting less than 24 hours attributable to
cerebral or retinal ischaemia

21
Q

What are the risk factors of TIA’s and strokes?

A
Family history
age
sex
smoking
diabetes
sickle cell
race
previous TIA's
22
Q

How does a TIA occur pathologically?

A

Causes: vascular i.e. large/small artery disease, cardiac embolism

23
Q

What are the signs and symptoms of TIA’s that can mimic other conditions?

A
Seizures
Syncope
Hypoglycaemia
Migraine
Acute confusional states
24
Q

How do you classify TIA’s?

A

Anterior or posterior circulation

25
Q

How does having a TIA affect the risk of having a stroke?

A
calculated via the ABCD(2) score
Age
BP
Clinical features
Duration symptoms
Diabetes
above 5 = high risk
26
Q

What investigations are conducted when a patient is suspected of a TIA?

A

History
Exam
Blood glucose

27
Q

What treatments are available for TIA’s?

A

Polypill - Combination of statin, aspirin, antihypertensives, folic acid
Carotid Endarterectomy - surgical procedure to unblock a carotid artery

28
Q

What are the signs and symptoms of a anterior circulation stroke?

A

Amarausis fugax - transient monocular or binocular visual loss
Dysphasia - cannot generate speech
Apraxia - inability to perform particular purposive actions
Inattention

29
Q

What are the signs and symptoms of a posterior circulation stroke?

A

Ataxia - the loss of full control of bodily movements
Diplopia - double vision
Vertigo
Bilateral Symptoms

30
Q

What are the signs and symptoms of a either anterior or posterior circulation stroke?

A

Visual field disturbance (e.g. hemianopia)
Hemiparesis - weakness of the entire left or right side of the body
Hemisensory loss
Dysarthria

31
Q

What is the definition of stroke?

A

Sudden onset
Focal neurological deficit
Of presumed vascular origin
Symptoms lasting more than 24 hours or leading to death

32
Q

What are the two types of stroke?

A

Ischemic - more common

Haemorrhagic

33
Q

What causes ischemic stroke?

A

Initial reduction in cerebral blood flow
Alterations in cellular chemistry caused by the ischaemia
Cellular necrosis

Thrombosis (large/small vessel)
Embolism (cardioembolism) - AF

34
Q

What causes haemorrhagic stroke?

A

Bleeding e.g. Berry Aneurysm

35
Q

What is the treatment for stroke?

A
Aspirin
Anticoagulation
Surgery e.g. endarterectomy (surgical removal of part of the inner lining of an artery), stent
Thrombolysis e.g. tPA
Recanalisation