Stroke and TIA Flashcards
A stroke in which the focal neurological deficits worsen with time
Also called a stroke in evolution
progressive stroke
A stroke in which the focal neurological deficits persist and do not worsen over time.
completed stroke
Clinical syndrome of rapid onset of focal deficits of brain function lasting more than 24 hours or leading to death
stroke
Clinical syndrome of rapid onset of focal deficits or brain function which resolves within 24 hours
Amaurosis fugax
RIND – 72 hours
TIA Transient Ischemic Attack
What is the most important risk factor for stroke?
previous TIA or stroke
What is the most prevalent risk factor for stroke?
hypertension
____ stroke is when blood leaks into brain tissue
hemorrhagic
____ stroke is when a clot stops blood supply to an area of the brain
ischemic
85% of strokes are ____
ischemic
What type of stroke accounts for 20% of all strokes?
thrombotic
5 classical lucunar syndromes:
- Pure _____ stroke/hemiparesis
- _____ hemiparesis
- Dysarthria/_____ hand
- Pure sensory
- Mixed sensorimotor
5 classical lucunar syndromes:
- Pure motor stroke/hemiparesis
- Ataxic hemiparesis
- Dysarthria/clumsy hand
- Pure sensory
- Mixed sensorimotor
Cardioembolic stroke
- Embolus from the heart gets _____ in the intracranial vessels
- ______ is most commonly affected
- ____ ______ is the most common cause
- Others: MI, prosthetic valves, rheumatic heart disease
Cardioembolic stroke
Embolus from the heart gets lodged in the intracranial vessels
MCA is most commonly affected
Atrial fibrillation is the most common cause
Others: MI, prosthetic valves, rheumatic heart disease
Artery to artery embolism
- Thrombus formed on atherosclerotic plaques gets embolized to ______ vessels
- Carotid ______ atherosclerosis is the most common source
- Others: aortic arch, vertebral arteries, etc.
Artery to artery embolism
- Thrombus formed on atherosclerotic plaques gets embolized to intracranial vessels
- Carotid bifurcation atherosclerosis is the most common source
- Others: aortic arch, vertebral arteries, etc.
Blood flow
If zero leads to death of brain tissue within _____ minutes (time is brain)
<_____ml/100g tissue per minute leads to infarction within and hour
Blood flow
If zero leads to death of brain tissue within 4-10 minutes (time is brain)
<16-18ml/100g tissue per minute leads to infarction within and hour
Ischemic Penumbra
Tissue surrounding the core region of the infarction which is ischemic but _____ dysfunctional
Maintained by ______
Can be salvaged if reperfused in time
Primary goal of revascularization therapies
Ischemic Penumbra
Tissue surrounding the core region of the infarction which is ischemic but reversibly dysfunctional
Maintained by collaterals
Can be salvaged if reperfused in time
Primary goal of revascularization therapies