Stroke Flashcards
what is a stroke?
- occurs when there is ischemia (inadequate blood flow) to part of the brain or hemorrhage into the brain that results in the death of brain cells
- “brain attack”
- time sensitive medical emergency
- longer =more damage
- 50,000 ppl in Canada have a stroke annually
what happens to the part of the brain that is affected by the stroke?
- functions such as movement, sensations, or emotions that were controlled by the affected area the brain are lost or impaired
- most ppl have mental or physical impairments after a stroke
what two major arteries supply the brain with blood?
- internal carotid arteries (2) -anterior circulation
- posterior vertebral arteries -posterior circulation
what is the worst type of stroke? (location)
basilar artery stokes are the worst because the circle of willis is cut off right at the beginning- so no blood flow is going to the brain whatsoever
what is connected at the circle of willis?
-the anterior and posterior cerebral circulation is connected at the circle of willis by the anterior and posterior communicating arteries
diagram of the blood flow to brain
look at notes bitsh if u wanna pass and move on with ur life
do it u piece of shit
why does the brain need a continuous supply of blood?
because it needs oxygen and glucose that neurons need to function
-brain has no where to store these things
if blood flow Is totally interrupted (cardiac arrest), how long does it take for neurological metabolism to be altered? metabolism? cellular death?
neurological metabolism:30 seconds
- metabolism stops in 2 min
- cellular death occurs in 5
- brain death can occur very quickly
-because the connection between arteries at the circle of willis, an area of brain can potentially receive blood supply from another blood vessel if its original blood supply is cut off (due to thrombus)
what is atherosclerosis?
- thickening and hardening of arteries
- major cause of ischemic stoke
- can lead to thrombus formation and contribute to emobli
- cerebral infraction occurs when a cerebral artery becomes blocked and blood supply to the brain beyond the blockage is occluded
- Wherever a clot is, the area distal to is does not have blood supply
where do MCA strokes come from?
the carotid artery
what are some NON modifiable risk factors for stroke?
- Age
- gender (more men than women)
- ethnicity
- family history
- Prior TIA increases risk of stroke by 50%
what are some modifiable risk factors for risk of stroke?
- Hypertension (single most important modifiable risk)
- Atrial fibrillation (left ventricle quivers and shakes causing stasis which can lead to clot)
- alcohol- thins blood, weakens vessels
- Physical inactivity- results in higher levels of inflammation, contributing to atherosclerotic development
- oral contraceptives (being greater than age 35 + smoking really increases risk)
what is an ischemic stroke?
-results from inadequate blood flow to the brain from partial or complete occlusion of an artery
-accounts for approx 80% of strokes
-
what are the two divisions of an ischemic stroke?
Thrombotic or embolic
what is a transient ischemic attack?
- A TIA is a transient episode of ischemia without acute infraction of the brain
- symptoms last less than 1 hour
- are a warning sign of cerebrovascular disease
- ppl tend to downplay things when the resolve on thier own
- TIA is usually a precursor for ischemic stroke
symptoms of a TIA?
- temporary loss of vision in one eye
- transient hemiparesis (paralysis of brain)
- inability to speak
- numbness or loss of sensation and vertigo
objective indications of TIA?
- CT or MRI
- ultrasounds on internal carotid
- bruit on auscultation if its on the carotid
what is a thrombotic stroke
- subtype of ischemic stroke
- occurs from injury to blood vessel wall and formation of a blood clot
- the lumen of the blood vessel becomes narrowed, and if it becomes occluded, infraction occurs
- symptoms may progress in the first 72 hrs as infraction and cerebral edema increase
what is the main difference between TIA and stroke?
- TIA occurs without infraction
- Stroke: infraction and cell death occurs
what is an embolic stroke?
- subtype of ischemic stroke
- occurs when an embolus lodges in and occludes a cerebral artery = infraction and edema of the area supplied by the blood vessel
- majority of emboli are from plaque breaking off from the endocardium
- (left atrium is the most common area it comes from)
- rapid onset of symptoms
- recurrence of embolic stroke is common unless underlying cause is aggressively treated (need to fix problem with heart of else it will just keep occurring)
what are some heart conditions that are associated with embolic stroke?
- valvular heart disease
- MI
- Endocarditis
- atrial fibrillation